Evaluationof in vivo toxicity of rice husk used as fuel for cooking in households

Mbassi Josiane Emilie Germaine, S. Ndindeng, Achu Mercy Bih Loh, Dimo Th eophile, Mbacham Fon Wilfred
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引用次数: 1

Abstract

This study meant to assess the toxicological impact of nourishment cooked or water overflowed with a fan-helped top-lit-updraft rice husk fuelled gasifier stove named Paul Olivier 150 (PO150). Refined water was bubbled for 1 h utilizing this stove in an opened pot and shut room. This water was then cooled to room temperature before being managed to the rodents with body loads going from 70 to 110 g. Two kinds of tests were performed: Acute and sub-chronic toxicity tests. For the acute toxicity study, an extraordinary portion of 2 ml/100 g body weight (BW) of bubbled water was managed orally to the rodents. The creatures were watched for harmful indications and mortality day by day for 14 days. In a sub-chronic toxicity study, the bubbled water, at dosages of 0.5, 1 and 2 ml/100 g BW were orally managed day by day for 28 days to rodents. Following 28 days, the rodents were yielded, Blood tests were gathered for hematological, biochemical and histological assessment. The control rodents were managed in refined water. The example of refined water overflowed with rice husk fuelled gasifier stove indicated no proof of single-portion toxicity (2 ml/100g) when studying acute toxicity. For the sub-chronic toxicity study, bubbled water at dosages of 0.5, 1 and 2 ml/100 g indicated huge contrast in certain parameters, for example, creatinine in guys (71.81 mg/dL), uric corrosive (2.75 mg/dL) and complete bilirubin (0.08 mg/dL), monocytes (0.49 103/µL)and granulocytes in females (2.70 103/µL) contrasted with the control gathering (64.16 mg/dL, 2.25 mg/dL, 0.19 mg/l, 0.37 103/µL and 1.80 103/µL for every parameter separately) however, the information did not ascend to the level for the responses to be viewed as a poisonous impact. These demonstrated that cooking in an open pot with a rice husk fuelled PO150 gasifier stove doesnot cause toxicity at the dosages considered.   Key words: Acute toxicity, sub-chronic toxicity, biochemical analysis, hematological parameters, histopathology, rice husk.
家用煮饭用稻壳的体内毒性评价
这项研究的目的是评估营养煮熟或水溢出的风扇帮助顶部升风稻壳燃料气化炉名为保罗奥利维尔150 (PO150)的毒理学影响。精炼水在一个打开的锅和封闭的房间里用这个炉子起泡1小时。然后将这些水冷却到室温,然后再给老鼠喂食,体重从70克到110克不等。进行了急性和亚慢性毒性试验。在急性毒性研究中,对啮齿动物口服2 ml/100 g体重(BW)的气泡水。在14天的时间里,每天观察这些动物的有害迹象和死亡率。在亚慢性毒性研究中,每天口服0.5、1和2 ml/100 g BW的泡泡水,持续28天。28 d后取鼠,采集血液进行血液学、生化和组织学检查。对照鼠类用精制水处理。精炼水溢出稻壳燃料气化炉的例子表明,在研究急性毒性时,没有证据表明单份毒性(2毫升/100克)。在亚慢性毒性研究中,泡泡水剂量为0.5、1和2 ml/100 g时,在某些参数上与对照组(分别为64.16 mg/dL、2.25 mg/dL、0.19 mg/ L、0.37 103/ L和1.80 103/ L)相比,男性肌酐(71.81 mg/dL)、尿酸(2.75 mg/dL)和完全胆红素(0.08 mg/dL)、单核细胞(0.49 103/ L)和粒细胞(2.70 103/ L)存在巨大差异。这些信息没有上升到反应被视为有害影响的程度。这些结果表明,在使用稻壳燃料PO150气化炉的开放式锅中烹饪,在所考虑的剂量下不会造成毒性。关键词:急性毒性,亚慢性毒性,生化分析,血液学参数,组织病理学,稻壳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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