Mbassi Josiane Emilie Germaine, S. Ndindeng, Achu Mercy Bih Loh, Dimo Th eophile, Mbacham Fon Wilfred
{"title":"Evaluationof in vivo toxicity of rice husk used as fuel for cooking in households","authors":"Mbassi Josiane Emilie Germaine, S. Ndindeng, Achu Mercy Bih Loh, Dimo Th eophile, Mbacham Fon Wilfred","doi":"10.5897/ajbr2020.1078","DOIUrl":null,"url":null,"abstract":"This study meant to assess the toxicological impact of nourishment cooked or water overflowed with a fan-helped top-lit-updraft rice husk fuelled gasifier stove named Paul Olivier 150 (PO150). Refined water was bubbled for 1 h utilizing this stove in an opened pot and shut room. This water was then cooled to room temperature before being managed to the rodents with body loads going from 70 to 110 g. Two kinds of tests were performed: Acute and sub-chronic toxicity tests. For the acute toxicity study, an extraordinary portion of 2 ml/100 g body weight (BW) of bubbled water was managed orally to the rodents. The creatures were watched for harmful indications and mortality day by day for 14 days. In a sub-chronic toxicity study, the bubbled water, at dosages of 0.5, 1 and 2 ml/100 g BW were orally managed day by day for 28 days to rodents. Following 28 days, the rodents were yielded, Blood tests were gathered for hematological, biochemical and histological assessment. The control rodents were managed in refined water. The example of refined water overflowed with rice husk fuelled gasifier stove indicated no proof of single-portion toxicity (2 ml/100g) when studying acute toxicity. For the sub-chronic toxicity study, bubbled water at dosages of 0.5, 1 and 2 ml/100 g indicated huge contrast in certain parameters, for example, creatinine in guys (71.81 mg/dL), uric corrosive (2.75 mg/dL) and complete bilirubin (0.08 mg/dL), monocytes (0.49 103/µL)and granulocytes in females (2.70 103/µL) contrasted with the control gathering (64.16 mg/dL, 2.25 mg/dL, 0.19 mg/l, 0.37 103/µL and 1.80 103/µL for every parameter separately) however, the information did not ascend to the level for the responses to be viewed as a poisonous impact. These demonstrated that cooking in an open pot with a rice husk fuelled PO150 gasifier stove doesnot cause toxicity at the dosages considered. \n \n \n \n Key words: Acute toxicity, sub-chronic toxicity, biochemical analysis, hematological parameters, histopathology, rice husk.","PeriodicalId":7631,"journal":{"name":"African Journal of Biochemistry Research","volume":"103 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Journal of Biochemistry Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5897/ajbr2020.1078","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
This study meant to assess the toxicological impact of nourishment cooked or water overflowed with a fan-helped top-lit-updraft rice husk fuelled gasifier stove named Paul Olivier 150 (PO150). Refined water was bubbled for 1 h utilizing this stove in an opened pot and shut room. This water was then cooled to room temperature before being managed to the rodents with body loads going from 70 to 110 g. Two kinds of tests were performed: Acute and sub-chronic toxicity tests. For the acute toxicity study, an extraordinary portion of 2 ml/100 g body weight (BW) of bubbled water was managed orally to the rodents. The creatures were watched for harmful indications and mortality day by day for 14 days. In a sub-chronic toxicity study, the bubbled water, at dosages of 0.5, 1 and 2 ml/100 g BW were orally managed day by day for 28 days to rodents. Following 28 days, the rodents were yielded, Blood tests were gathered for hematological, biochemical and histological assessment. The control rodents were managed in refined water. The example of refined water overflowed with rice husk fuelled gasifier stove indicated no proof of single-portion toxicity (2 ml/100g) when studying acute toxicity. For the sub-chronic toxicity study, bubbled water at dosages of 0.5, 1 and 2 ml/100 g indicated huge contrast in certain parameters, for example, creatinine in guys (71.81 mg/dL), uric corrosive (2.75 mg/dL) and complete bilirubin (0.08 mg/dL), monocytes (0.49 103/µL)and granulocytes in females (2.70 103/µL) contrasted with the control gathering (64.16 mg/dL, 2.25 mg/dL, 0.19 mg/l, 0.37 103/µL and 1.80 103/µL for every parameter separately) however, the information did not ascend to the level for the responses to be viewed as a poisonous impact. These demonstrated that cooking in an open pot with a rice husk fuelled PO150 gasifier stove doesnot cause toxicity at the dosages considered.
Key words: Acute toxicity, sub-chronic toxicity, biochemical analysis, hematological parameters, histopathology, rice husk.