Highlights of this issue

S. Suetani
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To me, the most striking finding of the study is not the occupational class suicide risk per se but the fact that the majority (83.4%) of 11 195 employed people who died of suicide were men. Surely, this is the inequality we need to address. How, then, do we prevent suicide? Can we eliminate suicide? The thought-provoking Analysis in this issue of BJPsych by Sjörstrand and Eyal (pp. 230–233) uses ethical principles to argue that aiming for zero may not be the best idea. The analysis reminds me of something that an emergency physician told me when I was an intern: ‘When someone dies of suicide, they kill themselves. The final decision to end the life is taken by the person who takes the life’. I remember feeling awfully uncomfortable with her statement, and I still do. Sjörstrand and Eyal argue that we ‘should fight the “fire” of social injustice instead of the “smoke” of suicide’. We do so by strengthening social and economic safety nets and extending universal access to healthcare and highquality mental health services. At the individual level, we should strive to identify psychosocial needs and offer person-centred care for psychiatric disorders and medical conditions. Yes, we are talking about good psychiatry practice, much like what is described in the WHO Mental Health Report (seamless prevention, mental health promotion and treatment services). One way to improve the quality of psychiatric care is to improve the way we evaluate our treatment options. A Mendelian randomisation study by Konzok et al (pp. 257–263) in this issue examines the bidirectional relationship between vitamin D and internalising disorders to find no evidence of any association. What is the Mendelian randomisation method? In essence, the method uses genetic variants to estimate causality unbiased by potential confounding factors. Unfortunately, the main downside of the study is that because the researchers used European data, the findings are not generalisable to a non-European like me. So, I continue to take my Vitamin D supplement every morning, still trying to figure out its benefit, wondering if this is an example of the significant gap between people in high-income countries and low-income countries that the WHO World Mental Health Report talks about. Another way to improve the quality of psychiatric care is to improve the precision of the tools that we use. Northwood et al (pp. 241–245) use receiver operating characteristic curve analysis of data from 294 individual participants from nine studies to determine the optimal clozapine level. Although this is not as sexy as the Mendelian randomisation method, their approach – using a robust mathematical model to solve a common clinical question – is both inspiring and impressive. The paper’s senior author was my last supervisor as I was finishing my psychiatry training. I would like to think that some of the conversations we had in our supervision sessions inspired him to conduct this impressive study. By the way, if you are wondering about the most optimal level for clozapine, it was lower than I expected – 372 ng/mL. Finally, in this issue, Byng et al (pp. 246–256) conduct a good old cluster randomised controlled trial to investigate the effectiveness of the PARTNERS2 programme in England. The programme incorporates person-centred coaching support and liaison work for people with diagnoses of psychotic disorders in the primary health sector. The programme does not improve the quality of life among the participants. Like vitamin D, something that makes intuitive sense isn’t always effective. What seems safe enough isn’t always sufficient. We must find other ways to identify psychosocial needs and offer person-centred care for people with psychotic disorders. How many calls for action does a man need, before he makes a change? Mental disorders are common and costly. We are blessed with many valuable tools in psychiatry: ethical principles, Mendelian randomisation and regular supervision sessions. We need to continue to harness different tools to improve our craft. We progress by testing ideas and rejecting ideologies. Can we sing along in harmony one more time? We need to change for the better. 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引用次数: 0

Abstract

A call for action is such an old song that we can sing along in harmony, and nowhere is it stronger than in psychiatry. Mental disorders are common and costly. We need to change for the better. In their editorial, Cujipers et al (pp. 227–229) outline the important take-home messages from the recently published World Health Organization (WHO) World Mental Health Report – another call for action – and urge us to galvanise our collective efforts. So how do we make a change? Take suicide, one of the priorities for change in the Report, as an example. Using the National Coronial Information System data in Australia, Burnett et al (pp. 234–240) investigate suicide rates by occupational class between 2007 and 2018. To me, the most striking finding of the study is not the occupational class suicide risk per se but the fact that the majority (83.4%) of 11 195 employed people who died of suicide were men. Surely, this is the inequality we need to address. How, then, do we prevent suicide? Can we eliminate suicide? The thought-provoking Analysis in this issue of BJPsych by Sjörstrand and Eyal (pp. 230–233) uses ethical principles to argue that aiming for zero may not be the best idea. The analysis reminds me of something that an emergency physician told me when I was an intern: ‘When someone dies of suicide, they kill themselves. The final decision to end the life is taken by the person who takes the life’. I remember feeling awfully uncomfortable with her statement, and I still do. Sjörstrand and Eyal argue that we ‘should fight the “fire” of social injustice instead of the “smoke” of suicide’. We do so by strengthening social and economic safety nets and extending universal access to healthcare and highquality mental health services. At the individual level, we should strive to identify psychosocial needs and offer person-centred care for psychiatric disorders and medical conditions. Yes, we are talking about good psychiatry practice, much like what is described in the WHO Mental Health Report (seamless prevention, mental health promotion and treatment services). One way to improve the quality of psychiatric care is to improve the way we evaluate our treatment options. A Mendelian randomisation study by Konzok et al (pp. 257–263) in this issue examines the bidirectional relationship between vitamin D and internalising disorders to find no evidence of any association. What is the Mendelian randomisation method? In essence, the method uses genetic variants to estimate causality unbiased by potential confounding factors. Unfortunately, the main downside of the study is that because the researchers used European data, the findings are not generalisable to a non-European like me. So, I continue to take my Vitamin D supplement every morning, still trying to figure out its benefit, wondering if this is an example of the significant gap between people in high-income countries and low-income countries that the WHO World Mental Health Report talks about. Another way to improve the quality of psychiatric care is to improve the precision of the tools that we use. Northwood et al (pp. 241–245) use receiver operating characteristic curve analysis of data from 294 individual participants from nine studies to determine the optimal clozapine level. Although this is not as sexy as the Mendelian randomisation method, their approach – using a robust mathematical model to solve a common clinical question – is both inspiring and impressive. The paper’s senior author was my last supervisor as I was finishing my psychiatry training. I would like to think that some of the conversations we had in our supervision sessions inspired him to conduct this impressive study. By the way, if you are wondering about the most optimal level for clozapine, it was lower than I expected – 372 ng/mL. Finally, in this issue, Byng et al (pp. 246–256) conduct a good old cluster randomised controlled trial to investigate the effectiveness of the PARTNERS2 programme in England. The programme incorporates person-centred coaching support and liaison work for people with diagnoses of psychotic disorders in the primary health sector. The programme does not improve the quality of life among the participants. Like vitamin D, something that makes intuitive sense isn’t always effective. What seems safe enough isn’t always sufficient. We must find other ways to identify psychosocial needs and offer person-centred care for people with psychotic disorders. How many calls for action does a man need, before he makes a change? Mental disorders are common and costly. We are blessed with many valuable tools in psychiatry: ethical principles, Mendelian randomisation and regular supervision sessions. We need to continue to harness different tools to improve our craft. We progress by testing ideas and rejecting ideologies. Can we sing along in harmony one more time? We need to change for the better. The British Journal of Psychiatry (2023) 222, A23. doi: 10.1192/bjp.2023.42
本期重点报道
号召行动是一首我们可以和谐合唱的老歌,而在精神病学领域,它的感染力最强烈。精神障碍很常见,而且代价高昂。我们需要向更好的方向改变。在他们的社论中,Cujipers等人(第227-229页)概述了最近出版的世界卫生组织(世卫组织)《世界精神卫生报告》(另一项行动呼吁)的重要信息,并敦促我们激发我们的集体努力。那么我们如何做出改变呢?以自杀为例,这是报告中改变的优先事项之一。Burnett等人(第234-240页)利用澳大利亚国家冠状信息系统的数据,调查了2007年至2018年间按职业类别划分的自杀率。对我来说,这项研究最引人注目的发现不是职业自杀风险本身,而是1195名死于自杀的雇员中,大多数(83.4%)是男性。当然,这就是我们需要解决的不平等问题。那么,我们该如何预防自杀呢?我们能消除自杀吗?Sjörstrand和Eyal在本期《BJPsych》上发表的一篇发人深省的分析文章(230-233页)运用伦理原则认为,以零为目标可能不是最好的主意。这一分析让我想起了实习时一位急诊医生告诉我的话:“当有人自杀身亡时,他们是在自杀。”结束生命的最终决定是由夺去生命的人做出的。”我记得我对她的话感到非常不舒服,现在仍然如此。Sjörstrand和Eyal认为,我们“应该与社会不公的‘火焰’作斗争,而不是与自杀的‘烟雾’作斗争”。为此,我们加强社会和经济安全网,普及医疗保健和高质量精神卫生服务。在个人层面,我们应努力确定心理社会需求,并为精神疾病和医疗状况提供以人为本的护理。是的,我们正在谈论良好的精神病学做法,就像世卫组织精神卫生报告中所描述的那样(无缝预防、精神卫生促进和治疗服务)。提高精神科护理质量的一种方法是改进我们评估治疗方案的方式。Konzok等人(第257-263页)在本期中进行的孟德尔随机化研究考察了维生素D与内化疾病之间的双向关系,但没有发现任何关联的证据。什么是孟德尔随机化方法?从本质上讲,该方法使用遗传变异来估计因果关系,而不受潜在混杂因素的影响。不幸的是,这项研究的主要缺点是,因为研究人员使用了欧洲的数据,所以研究结果不能推广到像我这样的非欧洲人身上。所以,我继续每天早上服用维生素D补充剂,仍然试图弄清楚它的好处,想知道这是否是世界卫生组织世界精神卫生报告中提到的高收入国家和低收入国家人民之间巨大差距的一个例子。另一种提高精神科护理质量的方法是提高我们使用的工具的精确度。Northwood等人(第241-245页)对来自9项研究的294名个体参与者的数据进行了受试者工作特征曲线分析,以确定最佳氯氮平水平。尽管这种方法不像孟德尔随机化方法那样性感,但他们的方法——利用一个强大的数学模型来解决一个常见的临床问题——既鼓舞人心又令人印象深刻。这篇论文的资深作者是我完成精神病学培训时的最后一位导师。我认为是我们在督导会议上的一些对话启发了他进行这项令人印象深刻的研究。顺便说一下,如果你想知道氯氮平的最佳水平,它比我预期的要低——372纳克/毫升。最后,在本期中,Byng等人(第246-256页)进行了一项很好的老式集群随机对照试验,以调查PARTNERS2计划在英国的有效性。该方案包括在初级保健部门为被诊断患有精神病的人提供以人为本的指导、支持和联络工作。该计划并没有提高参与者的生活质量。就像维生素D一样,直觉上的东西并不总是有效的。看起来足够安全的东西并不总是足够的。我们必须找到其他方法来确定心理社会需求,并为精神病患者提供以人为本的护理。一个人需要多少次号召才能做出改变?精神障碍很常见,而且代价高昂。我们有幸拥有许多有价值的精神病学工具:伦理原则、孟德尔随机化和定期监督会议。我们需要继续利用不同的工具来改进我们的技术。我们通过检验思想和摒弃意识形态而取得进步。我们能再一起和声唱一遍吗?我们需要向更好的方向改变。英国精神病学杂志(2023)222,A23。doi: 10.1192 / bjp.2023.42
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