A New Drimane from the Heartwood of the Japanese Yew, Taxus Cuspidata

Abstract

A new drimane sesquiterpenoid was isolated from the heartwood of the Japanese yew, Taxus cuspidata Sieb. et Zucc. Its structure was established as 1 g -acetoxyisodrimeninol (1 g -acetoxy-11,12-epoxy-7-drimen-11-ol, 1 ). This compound was gradually oxidized to give n -lactone (1 g -acetoxy-8-drimeno-11,12-lactone, 4 ).