Perspectives of the symposium “Hemapheresis”, held in Dordrecht, The Netherlands, 10 September 1987

L. Kater MD, PhD , J.Ph. Sybesma MD, PhD
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Abstract

The symposium “Haemapheresis” was held on 10 September 1987 in Dordrecht, The Netherlands, celebrating the 10th anniversary of the Blood Bank “Zuid-West Nederland”. Various aspects of donor and of therapeutic apheresis were discussed.

A main issue is the assessment of indications for the therapeutic use of haemapheresis. Haemapheresis has been attempted as a treatment modality in more than 150 diseases. In a report of the Health Council of the Netherlands “Therapeutic Haemapheresis” issued in 1986, categories have been described for indications (A-F):

  • &#x02022;

    • Category A pertained to an established indication fulfilling all criteria listed;

  • &#x02022;

    • Category B holds for an acceptable indication, which is fully proved;

  • &#x02022;

    • Category C is labelled, to be “an emergency indication”. This means that, although proof of efficacy is lacking, there are certain conditions in which haemapheresis cannot be withheld from a patient;

  • &#x02022;

    • Category D comprises diseases, in which the indication is not yet established and more randomised clinical trials are needed;

  • &#x02022;

    • Category E refers to more experimental indications for haemapheresis;

  • &#x02022;

    • Category F means that there is no indication for haemapheresis. Reports on therapeutic haemapheresis have to be considered within the framework of these guidelines.

In the presentations on donor apheresis an update was given on new developments in technology, including ways to obtain cell components and the side-effects and complications of the procedures.

1987年9月10日在荷兰多德雷赫特举行的“血液学”专题讨论会的观点
1987年9月10日在荷兰多德雷赫特举行了“血库”专题讨论会,以庆祝“西荷兰中部”血库成立十周年。讨论了供体单采和治疗单采的各个方面。一个主要的问题是对采血治疗用途的适应症的评估。采血术已被尝试作为一种治疗150多种疾病的方法。在1986年荷兰卫生委员会发布的一份“治疗性血湿”报告中,对适应症(a - f)进行了分类:#x02022;•a类指的是符合所列所有标准的既定适应症;#x02022;•B类指的是得到充分证明的可接受适应症;#x02022;•C类指的是“紧急适应症”。这意味着,尽管缺乏疗效证明,但在某些情况下,不能对患者进行抽血;•D类包括适应症尚未确定的疾病,需要进行更多的随机临床试验;•E类指的是更多的实验性抽血适应症;••F类指的是没有抽血适应症。关于治疗性血液病的报告必须在这些指南的框架内考虑。在关于供体采血的介绍中,介绍了技术的最新发展,包括获取细胞成分的方法以及该程序的副作用和并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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