{"title":"REGULATION OF BIOCATALYTIC PROPERTIES OF RHODOSPIRILLUM RUBRUM L-ASPARAGINASE BY THE FORMATION OF ENZYME CONJUGATES WITH POLYCATIONS","authors":"D. Zhdanov, N. Sokolov, E. Kudryashova","doi":"10.37747/2312-640x-2021-19-77-79","DOIUrl":null,"url":null,"abstract":"Covalent conjugates of asparaginase with copolymers of chitosan-PEG, chitosan-glycol and chitosan-PEI were obtained and their antitumor activity on human chronic myeloma leukemia K-562 cells was determined.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"54 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"http://eng.biomos.ru/conference/articles.htm","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37747/2312-640x-2021-19-77-79","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Covalent conjugates of asparaginase with copolymers of chitosan-PEG, chitosan-glycol and chitosan-PEI were obtained and their antitumor activity on human chronic myeloma leukemia K-562 cells was determined.