Autoimmune oophoritis: Clinical presentation of an unusual clinical entity

Abstract

Introduction Autoimmune oophoritis is a rare condition , which provokes ovarian failure with either primary amenorrhea or secondary amenorrhea and a subsequent loss of fertility and ovarian hormonal function. The purpose of this report is to document the clinical findings from two patients with aut-oimmune oophoritis. Cases report Two cases of autoimmune oophorit-is are presented whose histopathol-ogical findings were consistent with international literature. Both cases were histopathologically characteri-sed by lymphocytic and plasmacytic inflammatory infiltrations around the cystic follicles. The inflammation was located both in the theca and gr-anular layers. Conclusion Patients with autoimmune oophorit-is should be recognised by the histo-pathology of the ovarian biopsies as they are at an increased risk of developing other autoimmune disorders.