THE SIGNIFICANCE OF METICYLIN-RESISTANT STAPHYLOCOCCUS IN THE DEVELOPMENT OF SEPTIC INFECTIONS (IN THE MODEL OF PULMONARY INFLAMMATION/DESTRUCTION)

Abstract

Septic infections caused by methicillin-resistant Staphylococcus (MRS) are one of the most important challenges for modern medicine. The results of the study showed that MRS strains isolated from patients with pulmonary inflammation/destruction had much higher rates of antibiotic resistance compared to methicillin-sensitive Staphylococcus strains (MSS). At the same time, the clinical and socio-economic impact of patients with pulmonary inflammation with MRS is more significant compared to that of patients with MSS, requiring more expensive treatment over a longer period of time (13.81 days vs. 7.05 days) and more days of hospitalization (18.4 days vs. 11.3 days), including in the intensive care units (9.23 days vs. 2.25 days), as well as increased lethality (8.6% vs. 2.5 %).