Fatal Coronary Air Embolism during Positive Pressure Ventilation

Zahidi Ha, B. B, Arous S, B. G, Habbal R
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Abstract

We report the case of a 29 years old patient brought to emergency after a road traffic accident. His blood pressure was 138/78 mmHg, pulse 119/min, respiratory rate at 24/min and Glasgow coma scale at 6/15. The patient was put on mechanical ventilation then transferred to the intensive care unit. A body CT scan was performed which found multiple hemorraghic contusions and subarachnoid hemorrhage in the head. Lower right limb x-rays showed a mid diaphyseal femur fracture which then was surgically treated. 7 days after surgery, the patient suddenly developed hypotension, sinus tachycardia and acute respiratory distress. What is the most likely diagnosis at this stage?. Considering the patient condition, the most likely diagnosis was massive pulmonary embolism. Thorax CT scan was immediately performed which found coronary air embolism in circumflex artery as shown in figure 1. The high sensibility troponin level was 8900 ng/l. Barotrauma has been estimated to occur in 0.5-38% of critically ill patients [1]. Systemic and eventually coronary gas embolism associated with positive pressure ventilation has been considered a rare, but catastrophic complication of mechanical ventilation associated with a high mortality rate.
正压通气期间致死性冠状动脉空气栓塞
我们报告一例29岁的病人被带到紧急后的道路交通事故。血压138/78 mmHg,脉搏119/min,呼吸频率24/min,格拉斯哥昏迷评分6/15。病人先接受机械通气,然后转到重症监护病房。全身CT扫描发现头部多发出血性挫伤和蛛网膜下腔出血。右下肢x光片显示股骨骨干中段骨折,随后接受手术治疗。术后7天,患者突然出现低血压、窦性心动过速及急性呼吸窘迫。在这个阶段最可能的诊断是什么?考虑到病人的病情,最有可能的诊断是大面积肺栓塞。立即行胸部CT扫描,发现旋动脉冠状动脉空气栓塞,如图1所示。高敏感肌钙蛋白水平为8900 ng/l。据估计,0.5-38%的危重病人会发生气压创伤。与正压通气相关的系统性和最终冠状动脉气体栓塞被认为是一种罕见的,但具有高死亡率的灾难性机械通气并发症。
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