PENGARUH VARIASI BASIS GELLING AGENT TERHADAP KARAKTERISTIK FISIK MASKER GEL PEEL-OFF EKSTRAK DAUN PEPAYA (Carica papaya L.)

STIKes Mitra, Keluarga Jurnal, Mitra Kesehatan, Dena Sabela Pratiwi, Sisca Devi
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Abstract

Introduction: Acne is a chronic inflammation of the sebaceous glands due to inflammation and bacterial infection. One of the plants used to treat acne is papaya leaves (Carica papaya L.) because it has alkaloid compounds as antibacterial causes of acne. This study aims to determine the effect of gelling agent base variations on the physical characteristics of peel-off gel mask preparations and to determine the gelling agent base that produces the best physical characteristics of the preparation. Method: The method used was an experimental study using a completely randomized design (CRD) with three treatments and nine repetitions. Variations of the base gelling agent used were gelatin, CMC-Na, and carbopol 940. Each formula was tested for physical characteristics in the form of organoleptic tests, homogeneity, viscosity, spreadability, adhesion, drying time, and pH. Data analysis was carried out by testing for normality and homogeneity with the SPSS program. If the distribution of the resulting data shows normal and homogeneous, then the ANOVA test is used, while if it does not meet the normality and homogeneity requirements, the Kruskal-Wallis test is used with a 95% confidence level. Results: The resulting research shows that variations in the gelling agent gelatin, CMC-Na, and carbopol affect the physical characteristic test of papaya leaf extract peel-off gel masks in the form of pH, viscosity, adhesion, spreadability and drying time. Statistical results show that variations in gelling agents produce significant differences. Conclusion: Variations in gelling agent bases affect the physical characteristics of papaya leaf extract peel-off gel masks (Carica papaya L.) in the form of pH, viscosity, adhesion, spreadability and drying time of preparations. The gelling agent base that produces the best characteristics of papaya leaf extract (Carica papaya L.) peel-off gel mask preparation, namely gelling agent Karbopol 940 in formula 3 because it produces preparations that meet the requirements of all physical characteristic tests.
GELLING agents的各种变体对木瓜叶萃取物凝胶的生理特征的影响。
简介:痤疮是由于炎症和细菌感染引起的皮脂腺慢性炎症。其中一种用于治疗痤疮的植物是木瓜叶(Carica papaya L.),因为它含有生物碱化合物,可以抗菌痤疮。本研究旨在确定胶凝剂碱的变化对剥离式凝胶掩膜制剂物理特性的影响,并确定产生最佳物理特性的胶凝剂碱。方法:采用完全随机设计(CRD)的实验研究,3个处理,9个重复。使用的基础胶凝剂的变化是明胶,CMC-Na和卡波波尔940。采用感官测试、均匀性、粘度、涂抹性、粘附性、干燥时间和ph等方式对各配方进行物理特性测试。数据分析采用SPSS软件进行正态性和均匀性检验。如果结果数据的分布显示为正态和均匀,则使用方差分析检验,如果不满足正态和均匀性要求,则使用Kruskal-Wallis检验,置信水平为95%。结果:研究结果表明,凝胶剂明胶、CMC-Na和卡波醇的变化以pH值、黏度、粘附性、涂抹性和干燥时间的形式影响木瓜叶提取物剥脱凝胶面膜的物理特性测试。统计结果表明,胶凝剂的变化产生了显著的差异。结论:胶凝剂碱基的变化会影响木瓜叶提取物剥脱凝胶面膜(Carica papaya L.)的物理特性,主要表现在pH值、粘度、附着力、涂抹性和干燥时间等方面。产生木瓜叶提取物(Carica papaya L.)剥脱凝胶面膜制剂最佳特性的胶凝剂碱,即公式3中的胶凝剂Karbopol 940,因为它产生的制剂满足所有物理特性测试的要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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