Database for Development of the Cultured Neuronal Network

Abstract

It is generally assumed that the variability of neuronal firing pattern has an important effect on the connectivity of the nervous system, but this effect has not been thoroughly investigated. This challenging research area involves a tight cooperation of neuroscience, computer science, and biomedical engineering among others. In order to share our data and methods with the other experimenters and analysts, we have designed and implemented a database (http://bmp.hust.edu.cn/neuro_db/) including over 6000 GB data recorded from cultured neuronal networks on multi-electrode array. Most of these data were spontaneous activities of 50 cultures during development. The database presented here provides a crucial tool to explore neural development and neural coding, thus enables neuroscientists to share and manage data with greater efficiency. KeywordsNeuronal network; development; in vitro; multielectrode arrays