"Epigenetic Alterations: Epigenetics in Health and Disease. Impact of Deniplant Tea"

Gheorghe Giurgiu, M. Cojocaru
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Abstract

"Background Conditions such as cancers, metabolic disorders, psoriasis, and degenerative disorders have been found to be related to epigenetic alterations. Diet is one of the more easily studied, and therefore better understood, environmental factors in epigenetic change. Thus, an enhanced understanding of how epigenetic mechanisms modulate gene expression and how nutrition can optimize healthy epigenetic patterns can positively influence human health. The aim of the present project is to investigate whether a dietary intervention could ameliorate the clinical manifestations and modulate the epigenetic error in psoriatic disease. Materials and methods Nutrients could interact with the epigenome to ""protect or boost cognitive processes across the lifespan"". As we better understand the connections between diet and the epigenome, the opportunity arises for clinical applications in psoriasis. Results Recent studies have shown positive results for epigenetic-based therapies for psoriasis, which may be a field of increased focus in the coming years in search of better treatments. Deniplant tea can restore epigenetic alterations, resulting in amelioration or prevention of psoriasis and other systemic disease phenotypes, possibly also as a genetic modulator (CARD14 gene). The authors made EGO-Deniplant an online program for food control, modulating symptoms in psoriasis. Conclusion Epigenetic alterations have given insight into the understanding of the pathophysiology of psoriatic disease."
表观遗传改变:健康与疾病中的表观遗传学。“脱植茶”的影响
癌症、代谢紊乱、牛皮癣和退行性疾病等疾病已被发现与表观遗传改变有关。饮食是表观遗传变化中比较容易研究、因此也比较容易理解的环境因素之一。因此,增强对表观遗传机制如何调节基因表达以及营养如何优化健康表观遗传模式的理解可以对人类健康产生积极影响。本项目旨在探讨饮食干预是否可以改善银屑病的临床表现并调节表观遗传错误。营养物质可以与表观基因组相互作用,“保护或促进整个生命周期的认知过程”。当我们更好地理解饮食和表观基因组之间的联系时,牛皮癣的临床应用就有了机会。最近的研究显示,基于表观遗传学的银屑病治疗取得了积极的结果,这可能是未来几年寻找更好治疗方法的一个重点领域。脱植物茶可以恢复表观遗传改变,从而改善或预防牛皮癣和其他全身性疾病表型,也可能作为遗传调节剂(CARD14基因)。作者制作了EGO-Deniplant在线程序,用于控制食物,调节牛皮癣症状。结论表观遗传改变为理解银屑病的病理生理学提供了新的思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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