Manifestaciones dermatológicas en una lactante con síndrome de kwashiorkor: Claves para el diagnóstico y tratamiento oportuno

Kevin Alexis Hernández Lara, María Teresa García Romero, Alejandra Olvera Suarez, Nuria Francisco Revilla Estivillo
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Abstract

Kwashiorkor syndrome is characterized by protein malnutrition and edema, risk factors are recent weaning, infections, and diets based on corn and rice. This malnutrition can lead to skin manifestations such as thin, dry skin, hyperpigmentation, confluent areas of scaling, dry, hypopigmented, and detachable hair, as well as erosive dermatitis, predominantly in skin folds. The diagnosis is based on a nutritional evaluation exam, physical examination and laboratory finding, the treatment is based on early nutritional rehabilitation. Clinical case: 8-month-old female infant who attended the Instituto Nacional de Pediatría, presenting a scaling dermatosis of 1 months of evolution that was treated with topical ketoconazole. The mother reported exclusive feeding with corn gruel due to the diagnosis of “lactose allergy” and commented not enough resources to buy hydrolyzed formula. The patient presented a disseminated dermatosis to all- body segments, characterized by well-defined, irregularly shaped, hyperpigmented plaques with scaling in thick sheets in the perioral region and extremities, as well as areas of eroded skin and paleness and edema of extremities. Laboratory tests were taken, where anemia (Hb 11.2 g/dl) and hypoalbuminemia (3.3 g/dl) were documented, the diagnosis of Kwashiorkor syndrome was integrated. The clinical and laboratory findings were reported to the Gastroenterology and Nutrition service, who performed a nutritional assessment, and began nutritional treatment, emollients and general skin care were documented; twenty days later, the dermatosis and edema had subsided. Keywords: Malnutrition; dermatoses; edema; feeding; desquamation.
夸希奥科综合征婴儿的皮肤表现:诊断和及时治疗的关键
夸希奥尔克尔综合征的特征是蛋白质营养不良和水肿,危险因素是最近断奶、感染和以玉米和大米为基础的饮食。这种营养不良可导致皮肤表现,如皮肤薄、干燥、色素沉着、结痂、头发干燥、色素沉着和可脱落,以及主要发生在皮肤褶皱处的糜烂性皮炎。诊断是基于营养评估检查,体格检查和实验室发现,治疗是基于早期营养康复。临床病例:8个月大的女婴就诊于国立医院Pediatría,表现为发展1个月的鳞屑皮肤病,外用酮康唑治疗。这位母亲报告说,由于诊断为“乳糖过敏”,她只能用玉米粥喂养,并表示没有足够的资源购买水解配方奶粉。患者表现为弥散性皮肤病,遍及全身各节,其特征是口腔周围和四肢出现界限分明、形状不规则、色素沉着的斑块,并有厚厚的鳞屑,以及皮肤侵蚀、四肢苍白和水肿。进行了实验室检查,记录了贫血(Hb 11.2 g/dl)和低白蛋白血症(3.3 g/dl),合并了夸希奥克尔综合征的诊断。临床和实验室结果报告给胃肠病学和营养服务,他们进行营养评估,并开始营养治疗,润肤剂和一般皮肤护理记录;20 d后,皮肤病和水肿消退。关键词:营养不良;皮肤病;水肿;喂养;脱屑。
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