Correlation between Short Stature with Serum Ferritin Levels in Major Beta-Thalassemia Patients at Kediri District General Hospital

IF 0.7 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Grafita Dwi Kartikasari, Chasan Ismail
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引用次数: 0

Abstract

In thalassemia, a lifelong sequence of blood transfusions leads to iron overload characterized by increased ferritin levels. Many factors, including iron overload may cause growth delay. High ferritin levels are believed to lead to short stature in children with thalassemia. This study aims to determine the correlation between short stature and ferritin levels in children with major beta thalassemia at Kediri District General Hospital. This research is an observational analytic with a cross-sectional design conducted on 17 subjects of beta thalassemia major patients at Pediatric Health Sciences (IKA) Kediri District General Hospital who met the inclusion and exclusion criteria in December 2022-January 2023. The measuring instrument used in this study was anthropometric status, explained through age stature, while the ferritin levels was obtained from the patient's medical record. Spearman's rank order correlation test was used in the analysis. There were 17 respondents, 82,36% children in short categories and 17,64% in normal categories. The Spearman correlation test has the p-value = 0.000 and r = -0,736. A strong negative correlation exists between short stature and ferritin levels in beta-thalassemia major patients at Kediri District General Hospital that means the higher ferritin levels, the higher incidence rate of short stature.
Kediri地区总医院主要β -地中海贫血患者身材矮小与血清铁蛋白水平的相关性
在地中海贫血中,终生的输血顺序导致铁超载,其特征是铁蛋白水平升高。许多因素,包括铁超载可能导致生长迟缓。高铁蛋白水平被认为会导致地中海贫血儿童身材矮小。本研究旨在确定Kediri地区总医院患有严重β -地中海贫血的儿童身材矮小与铁蛋白水平之间的关系。本研究是一项横断面设计的观察性分析,研究对象为儿科健康科学(IKA) Kediri区总医院的17例符合纳入和排除标准的β地中海贫血主要患者,研究时间为2022年12月至2023年1月。本研究中使用的测量工具是人体测量状态,通过年龄和身高来解释,而铁蛋白水平则从患者的医疗记录中获得。分析采用Spearman秩序相关检验。调查对象17人,短类别儿童82.36%,正常类别儿童17.64%。Spearman相关检验的p值= 0.000,r = - 0.736。Kediri区总医院β -地中海贫血重症患者的身材矮小与铁蛋白水平之间存在很强的负相关,这意味着铁蛋白水平越高,身材矮小的发病率越高。
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来源期刊
International Journal of Migration Health and Social Care
International Journal of Migration Health and Social Care PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.30
自引率
0.00%
发文量
21
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