Genom and Gene Mutation of SARS-CoV-2

Edy Parwanto
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Abstract

The SARS-CoV-2 genome consists of the: 5’ UTR, ORF 1ab gene, S gene, ORF 3a gene, E gene, M gene, ORF 6 gene, ORF 7a gene, ORF 7b gene, ORF 8 gene, N gene, ORF 10 gene and 3’ UTR. Gene mutations in SARS-CoV-2 can occur in all genes that make up the genome of SARS-CoV-2. Due to mutations in the SARS-CoV-2 gene, various variants of SARS-CoV-2 appear. Several variants of SARS-CoV-2 recorded since December 2020 include of B.1.1.7, B.1.351, B. 1.429, B.1.1.28, B.1.617 and B.1.618 variants. Due to the emergence of various variants of SARS-CoV-2, we must be more careful to avoid COVID-19. People who have co-morbidities of COVID-19 should be more careful to avoid COVID-19. We must continue to apply health protocols at the community level to prevent the transmission of SARS-CoV-2
SARS-CoV-2的基因组及基因突变
SARS-CoV-2基因组由:5′UTR、ORF 1ab基因、S基因、ORF 3a基因、E基因、M基因、ORF 6基因、ORF 7a基因、ORF 7b基因、ORF 8基因、N基因、ORF 10基因和3′UTR组成。SARS-CoV-2的基因突变可能发生在构成SARS-CoV-2基因组的所有基因中。由于SARS-CoV-2基因的突变,出现了各种SARS-CoV-2变异。自2020年12月以来记录的几种SARS-CoV-2变体包括B.1.1.7、B.1.351、B. 1.429、B.1.1.28、B.1.617和B.1.618变体。由于SARS-CoV-2的各种变体的出现,我们必须更加小心避免COVID-19。患有COVID-19合并症的人应更加小心避免COVID-19。我们必须继续在社区层面实施卫生方案,以防止SARS-CoV-2的传播
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