Prediction of osmotic airway hyperresponsiveness in patients with bronchial asthma using adaptive neuro-fuzzy network

Abstract

The paper discusses the development of decision support systems based on adaptive neuro-fuzzy network to predict the osmotic airway hyperreactivity in patients with bronchial asthma. Static spirography data analysis has been conducted and polymorphism in the TRPV4 gene examined. A prediction system comprising the parts of pre-processing and neuro-fuzzy inference has been developed. A GUI has been implemented for the system. MATLAB is used as the modeling and computation engine.