High strength graphene oxide/polyvinyl alcohol composite hydrogels

IF 6.1 3区医学 Q1 MATERIALS SCIENCE, BIOMATERIALS

Journal of Materials Chemistry B Pub Date : 2011-07-05 DOI:10.1039/C0JM04043F

Lu Zhang, Zhipeng Wang, Chen Xu, Yi Li, Jian-ping Gao, Wen Wang, Yu Liu

引用次数: 362

Abstract

Polyvinyl alcohol (PVA) hydrogels have been proposed for use as promising biomaterials in biomedical and tissue engineering but their poor mechanical and water-retention properties have hindered their development. Graphene oxide (GO), an excellent nanofiller, was added to PVA to make GO/PVA composite hydrogels by a freeze/thaw method. The mechanical properties of the GO/PVA hydrogels were significantly improved. Compared to pure PVA hydrogels, a 132% increase in tensile strength and a 36% improvement of compressive strength were achieved with the addition of 0.8 wt% of GO, which suggests an excellent load transfer between the GO and the PVA matrix. The incorporation of certain amount of GO into composite hydrogels does not affect the toxicity of PVA to osteoblast cells.

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高强度氧化石墨烯/聚乙烯醇复合水凝胶

聚乙烯醇(PVA)水凝胶是一种很有前途的生物材料，可用于生物医学和组织工程领域，但其较差的力学性能和保水性阻碍了其发展。将优异的纳米填料氧化石墨烯(GO)加入到PVA中，采用冷冻/解冻法制备了氧化石墨烯/PVA复合水凝胶。氧化石墨烯/聚乙烯醇水凝胶的力学性能得到了显著改善。与纯PVA水凝胶相比，添加0.8 wt%的氧化石墨烯可提高132%的抗拉强度和36%的抗压强度，这表明氧化石墨烯和PVA基质之间具有良好的负载传递。在复合水凝胶中掺入一定量的氧化石墨烯并不影响聚乙烯醇对成骨细胞的毒性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Materials Chemistry B MATERIALS SCIENCE, BIOMATERIALS-

CiteScore

11.50

自引率

4.30%

发文量

866

期刊介绍： Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive： Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices