Correlation study of relative parameters of intracranial pressure and prognosis of patient with craniocerebral injury

Abstract

Objective: To analyze the correlation of the relative parameters of intracranial pressure to the prognosis in patients with craniocerebral injury.Methods: The clinical data of 80 patients with closed craniocerebral injury were retrospectively analyzed, and all of these patients underwent conventional examinations of arterial blood pressure and intracranial pressure. Neumatic DCR system was used to monitor relative parameters of intracranial pressure from patients. According to the score of Glasgow outcome scale (GOS) upon discharge, they were divided into favorable prognosis group (GOS III-V, n = 46) and unfavorable prognosis group (GOS I-II, n = 34). The relative parameters of intracranial pressure of two groups were compared so as to analyze the correlation of the prognosis in patients to ICP-related parameters.Results: Pressure reactivity index (PRx) and intracranial pressure (ICP) of favorable prognosis group were significantly higher than those of unfavorable prognosis group (t = 12.27, t = 5.22, p < .05). Meanwhile, cerebral perfusion pressure (CPP) and ICP-ABP wave amplitude correlation (IAAC) of favorable prognosis group were significantly lower than those of unfavorable prognosis group (t = 14.54, t = 14.78, p < .05). The average age, gender, duration of admission to neurosurgical intensive care unit (NICU) and GCS (Glasgow coma scale) score on admission of the two groups were not statistically significant.Conclusions: The prognosis and ICP-related parameters (such as PRx, ICP, CPP, etc.) in patients with craniocerebral injury are risk factors for the prognosis effect. Therefore, to monitor the above-mentioned indicators has an important clinical value for assessing the prognosis of craniocerebral injury.