RESEARCH, CASUISTRY AND PSYCHIATRY - AN ASIAN PERSPECTIVE

IF 0.1 Q4 PSYCHIATRY
N. Robson., S. Jambunathan, J. Gill, A. Sulaiman, M. H. Habil
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Abstract

Dear Sirin a recent article published in your journal, Volume 10 (1): Jan-June 2009, Vaingankar et. al, (2009) reported an elegant article on „Psychiatric research and ethics: Attitudes of mental healthcare professionals in Singapore‟ [1]. We would like to respond to the article by sharing our thoughts and experience on intention, autonomy, casuistry and psychiatric research from an Asian perspective. Over the last decade research in Asia has increased dramatically. This is mainly due to awareness regarding great research potential and also pharmaceutical interests in Asian population [2]. The increasing number of trials have generated a need to ensure that participants in clinical trials were protected and that data reported were valid [3]. Thus adhering to standard international guideline such as Good Clinical Practice (GCP) served this purpose [4, 5]. Conducting research involving patients with psychological problems can be controversial if GCP principles are not adhered to strictly. Many questions arise with regards to proper informed consent, protocol violation and post-research followup care. Another influential factor for research in psychiatry in Asia is the rich multi-cultural population that has varying attitudes and beliefs towards psychological problems and the treatment options [6-8]. Culture bound syndromes, often treated holistically by the traditional healer may lose this option where clinical trials readily offer a purely reductionistic pharmacological form of treatment for conditions involving the mind and not only the brain, and that may require not just medication.
研究、诡辩与精神病学——亚洲视角
亲爱的Sirin,最近在你的杂志上发表的一篇文章,第10卷(1):2009年1 - 6月,Vaingankar et. al,(2009)报道了一篇优雅的文章“精神病学研究和伦理:新加坡精神卫生保健专业人员的态度”[1]。我们想回应这篇文章,从亚洲的角度分享我们对意图、自主、诡辩和精神病学研究的想法和经验。在过去的十年里,亚洲的研究急剧增加。这主要是由于亚洲人群对巨大的研究潜力和药物兴趣的认识[2]。随着试验数量的增加,有必要确保临床试验的参与者受到保护,并且报告的数据是有效的[3]。因此,遵循国际标准指南,如良好临床实践(GCP),就达到了这一目的[4,5]。如果不严格遵守GCP原则,进行涉及心理问题患者的研究可能会引起争议。在适当的知情同意、违反协议和研究后随访护理方面出现了许多问题。亚洲精神病学研究的另一个影响因素是丰富的多元文化人口,他们对心理问题和治疗方案有着不同的态度和信念[6-8]。通常由传统治疗师进行整体治疗的文化束缚综合征可能会失去这种选择,因为临床试验很容易为涉及精神而不仅仅是大脑的疾病提供纯粹简化的药理学治疗形式,并且可能不仅仅需要药物治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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