Penggunaan CONUT Score sebagai Prediktor Komplikasi Pasca Pem-bedahan Kanker Kolorektal di RSUP Prof. Dr. R. D. Kandou Manado

JURNAL BIOMEDIK (JBM) Pub Date : 2019-03-04 DOI:10.35790/JBM.11.1.2019.23212

Hendry Sundah, Toar Mambu, Ferdinand Tjandra, Heber B. Sapan, Winfrid M. Sumanti

{"title":"Penggunaan CONUT Score sebagai Prediktor Komplikasi Pasca Pem-bedahan Kanker Kolorektal di RSUP Prof. Dr. R. D. Kandou Manado","authors":"Hendry Sundah, Toar Mambu, Ferdinand Tjandra, Heber B. Sapan, Winfrid M. Sumanti","doi":"10.35790/JBM.11.1.2019.23212","DOIUrl":null,"url":null,"abstract":"Abstract: Nutritional status is one of the factors that influence the metabolic and physiological conditions. Cancer patients, especially colorectal cancer (CRCA), will suffer from decreased nutritional status during their sickness. CONUT score is beneficial to evaluate the nutritional and immunity status of the patients and has been proved to correlate with post operative complications and length of stay. This study was aimed to evaluate the relationship between CONUT score and postoperative complications in CRCA patients. This was an analytical observational study with a cross sectional design. Subjects were 38 patients of CRCA that underwent operation and were admitted at Surgery Inpatients Installation of Prof. Dr. R. D. Kandou Hospital Manado. The result of logistic regression analysis indicated that there was a significant correlation between CONUT score and the risk of complication. The higher the CONUT score, the higher the risk of complication. The determination of complication diagnostic value based on CONUT score was obtained by using ROC curve. The ROC analysis showed that the AUC of CONUT score was 0.977 >0.700 and the cutoff point of CONUT score was 5.5. Patients with CONUT score >5.50 had a tendency to get postoperative complications with the sensitivity of 86.6%, specifity of 95.6%, and accuracy of 94.74%. Conclusion: CONUT score can be used as a screening method to predict the occurence of postoperative complications in CRCA patients.Kata kunci: colorectal cancer, CONUT score, postoperative complicationsAbstrak: Salah satu faktor yang memengaruhi keadaan metabolik dan fisiologik ialah status nutrisi. Penderita kanker terlebih kanker kolorektal (KKR) akan mengalami pengurangan nutrisi selama perjalanan penyakit. CONUT score bermanfaat untuk mengevaluasi status gizi dan imunitas pasien serta terbukti berkolerasi dengan komplikasi serta jumlah hari rawat di rumah sakit pasca pembedahan. Penelitian ini bertujuan untuk mengetahui hubungan CONUT score dengan komplikasi pasca pembedahan KKR. Jenis penelitian ialah analitik obser-vasional dengan desain potong lintang. Subyek penelitian ialah 38 pasien KKR yang menjalani operasi dirawat di Instalasi Rawat Inap Bedah RSUP Prof. Dr. R. D. Kandou Manado. Hasil analisis regresi logistik menyatakan terdapat hubungan yang sangat bermakna antara CONUT score dan kejadian komplikasi. Hubungan ini menyatakan bahwa makin tinggi CONUT score makin besar risiko terjadinya komplikasi. Penentuan nilai diagnostik kom-plikasi berdasarkan CONUT score diperoleh melalui kurva ROC. Berdasarkan analisis ROC diperoleh AUC CONUT score 0,977 >0,700. Hasil analisis ROC memperoleh titik potong CONUT score = 5,5. Pasien dengan CONUT score >5,50 memiliki kecenderungan mengalami komplikasi dengan sensitivitas 86,6%, spesifitas 95,6%, dan nilai akurasi 94,74%. Simpulan: CONUT score dapat digunakan sebagai metode skrining untuk memrediksi terjadinya komplikasi pasca pembedahan kanker kolorektal.Kata kunci: karsinoma kolorektal (KKR), CONUT score, komplikasi pasca pembedahan","PeriodicalId":17726,"journal":{"name":"JURNAL BIOMEDIK (JBM)","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JURNAL BIOMEDIK (JBM)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35790/JBM.11.1.2019.23212","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Abstract: Nutritional status is one of the factors that influence the metabolic and physiological conditions. Cancer patients, especially colorectal cancer (CRCA), will suffer from decreased nutritional status during their sickness. CONUT score is beneficial to evaluate the nutritional and immunity status of the patients and has been proved to correlate with post operative complications and length of stay. This study was aimed to evaluate the relationship between CONUT score and postoperative complications in CRCA patients. This was an analytical observational study with a cross sectional design. Subjects were 38 patients of CRCA that underwent operation and were admitted at Surgery Inpatients Installation of Prof. Dr. R. D. Kandou Hospital Manado. The result of logistic regression analysis indicated that there was a significant correlation between CONUT score and the risk of complication. The higher the CONUT score, the higher the risk of complication. The determination of complication diagnostic value based on CONUT score was obtained by using ROC curve. The ROC analysis showed that the AUC of CONUT score was 0.977 >0.700 and the cutoff point of CONUT score was 5.5. Patients with CONUT score >5.50 had a tendency to get postoperative complications with the sensitivity of 86.6%, specifity of 95.6%, and accuracy of 94.74%. Conclusion: CONUT score can be used as a screening method to predict the occurence of postoperative complications in CRCA patients.Kata kunci: colorectal cancer, CONUT score, postoperative complicationsAbstrak: Salah satu faktor yang memengaruhi keadaan metabolik dan fisiologik ialah status nutrisi. Penderita kanker terlebih kanker kolorektal (KKR) akan mengalami pengurangan nutrisi selama perjalanan penyakit. CONUT score bermanfaat untuk mengevaluasi status gizi dan imunitas pasien serta terbukti berkolerasi dengan komplikasi serta jumlah hari rawat di rumah sakit pasca pembedahan. Penelitian ini bertujuan untuk mengetahui hubungan CONUT score dengan komplikasi pasca pembedahan KKR. Jenis penelitian ialah analitik obser-vasional dengan desain potong lintang. Subyek penelitian ialah 38 pasien KKR yang menjalani operasi dirawat di Instalasi Rawat Inap Bedah RSUP Prof. Dr. R. D. Kandou Manado. Hasil analisis regresi logistik menyatakan terdapat hubungan yang sangat bermakna antara CONUT score dan kejadian komplikasi. Hubungan ini menyatakan bahwa makin tinggi CONUT score makin besar risiko terjadinya komplikasi. Penentuan nilai diagnostik kom-plikasi berdasarkan CONUT score diperoleh melalui kurva ROC. Berdasarkan analisis ROC diperoleh AUC CONUT score 0,977 >0,700. Hasil analisis ROC memperoleh titik potong CONUT score = 5,5. Pasien dengan CONUT score >5,50 memiliki kecenderungan mengalami komplikasi dengan sensitivitas 86,6%, spesifitas 95,6%, dan nilai akurasi 94,74%. Simpulan: CONUT score dapat digunakan sebagai metode skrining untuk memrediksi terjadinya komplikasi pasca pembedahan kanker kolorektal.Kata kunci: karsinoma kolorektal (KKR), CONUT score, komplikasi pasca pembedahan

查看原文本刊更多论文

康定得分疗法是RSUP教授坎杜·马纳多癌症后并发症的预测结果

摘要:营养状况是影响机体代谢和生理状况的因素之一。癌症患者，特别是结直肠癌(CRCA)，在患病期间营养状况会下降。CONUT评分有利于评估患者的营养和免疫状况，并已被证明与术后并发症和住院时间相关。本研究旨在评估CRCA患者CONUT评分与术后并发症的关系。这是一项采用横断面设计的分析性观察研究。研究对象是在万鸦老Dr. Dr. Kandou医院外科住院部接受手术治疗的38例CRCA患者。logistic回归分析结果显示CONUT评分与并发症发生风险有显著相关。CONUT评分越高，并发症的风险越高。采用ROC曲线确定CONUT评分对并发症的诊断价值。ROC分析显示，CONUT评分的AUC为0.977 ~ 0.700,CONUT评分的截断点为5.5。CONUT评分> - 5.50的患者易发生术后并发症，敏感性为86.6%，特异性为95.6%，准确性为94.74%。结论:CONUT评分可作为预测CRCA患者术后并发症发生的筛查方法。结直肠癌、CONUT评分、术后并发症摘要:Salah状态因子对阳门癌的影响、代谢、病理及营养状况的影响。Penderita kanker terlebih kanker kolorektal (KKR) akan mengalami pengurangan nutrisi selama perjalanan penyakit。CONUT评分:人类免疫系统的健康状况评估:人类免疫系统的健康状况评估:人类免疫系统的健康状况评估:人类免疫系统的健康状况评估:人类免疫系统的健康状况评估:人类免疫系统。Penelitian ini bertujuan untuk mengetahui hubungan CONUT score dengan komplikasi pasca penpendahan KKR。詹尼斯·佩内利特是一名分析观察家，也是一名职业登记者。Subyek penelitian ialah 38 pasien KKR yang menjalani operasi dirawat di Instalasi Rawat Inap Bedah RSUP教授Dr. D. Kandou Manado博士。基于logistic回归分析的数据分析与数据分析。Hubungan ini menyatakan bahwa making tinggi CONUT score making besar risiko terjadinya komplikasi。Penentuan nilai诊断komk -plikasi berdasarkan cont评分与ROC比较。Berdasarkan分析ROC diperoleh AUC CONUT得分为0,977 ~ 0,700。Hasil分析结果显示，受试者的ROC评分为55,5分。紫癜性丹参CONUT评分为0.55,0.50，紫癜性丹参敏感性86.6%，特异性95.6%，紫癜性丹参94.74%。猴:CONUT score dapat digunakan sebagai方法skrining untuk memredksi terjadinya komplikasi pasca pemobdahan kanker kolorektal。kapata kunci: karsinoma kolorektal (KKR)， CONUT评分，komplikasi pasca pempdahan

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

JURNAL BIOMEDIK (JBM)

自引率

0.00%

发文量