The Role of Melatonin in Improving Clinical Responses of Chemotherapy in Solid Cancer Patients: A Systematic Review

Abstract

It is common for patient undergoing cancer treatment to consume any kind of supplement in order to enhance treatment efficacy or minimize side effects. There are many supplementations available out there including antioxidant which is used by approximately 22-83% cancer patients [1-3]. This group of antioxidant includes N-acetylcysteine, glutathione, vitamin A, vitamin C, vitamin E, beta carotene, melatonin, and many others. The one which has been explored by many researchers is melatonin (MLT).