L. P. Mai, D. Guénard, M. Fránck, M. Van Tri, C. Gaspard, T. Sévenet
{"title":"New Cytotoxic Cucurbitacins from the Pericarps of Trichosanthes Tricuspidata Fruits","authors":"L. P. Mai, D. Guénard, M. Fránck, M. Van Tri, C. Gaspard, T. Sévenet","doi":"10.1080/1057563029001/4755","DOIUrl":null,"url":null,"abstract":"An extract of the fruits of Trichosanthes tricuspidata collected in North Vietnam was found cytotoxic in KB cells. A bioassay-guided fractionation led to the isolation of a series of cucurbitacins of which two are new:tricuspidatin and 2-O-glucocucurbitacin J. Their isolation and structure determination are described.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/1057563029001/4755","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
An extract of the fruits of Trichosanthes tricuspidata collected in North Vietnam was found cytotoxic in KB cells. A bioassay-guided fractionation led to the isolation of a series of cucurbitacins of which two are new:tricuspidatin and 2-O-glucocucurbitacin J. Their isolation and structure determination are described.