New Cytotoxic Cucurbitacins from the Pericarps of Trichosanthes Tricuspidata Fruits

L. P. Mai, D. Guénard, M. Fránck, M. Van Tri, C. Gaspard, T. Sévenet
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引用次数: 18

Abstract

An extract of the fruits of Trichosanthes tricuspidata collected in North Vietnam was found cytotoxic in KB cells. A bioassay-guided fractionation led to the isolation of a series of cucurbitacins of which two are new:tricuspidatin and 2-O-glucocucurbitacin J. Their isolation and structure determination are described.
从Tricuspidata果实果皮中提取新的细胞毒性葫芦素
在越南北部收集的tricuspidata果实提取物被发现对KB细胞有细胞毒性。用生物测定法分离了一系列葫芦素,其中两种是新发现的:三葡萄糖苷和2- o -糖葫芦素j。
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