Assertive Community Treatment For People With Alcohol Dependence: A Pilot Randomized Controlled Trial

C. Drummond, H. Gilburt, T. Burns, A. Copello, M. Crawford, E. Day, P. Deluca, C. Godfrey, S. Parrott, A. Rose, J. Sinclair, S. Coulton
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引用次数: 20

Abstract

Abstract Aims A pilot randomized controlled trial (RCT) to assess the feasibility and potential efficacy of assertive community treatment (ACT) in adults with alcohol dependence. Methods Single blind, individually randomized, pilot RCT of 12 months of ACT plus treatment as usual (TAU) versus TAU alone in adults (age 18+ years) with alcohol dependence and a history of previous unsuccessful alcohol treatment attending specialist community alcohol treatment services. ACT aimed to actively engage participants for 12 months with assertive, regular, minimum weekly contact. ACT was combined with TAU. TAU comprised access to the full range of services provided by the community teams. Primary outcome is mean drinks per drinking day and percent days abstinent at 12 months follow up. Analysis of covariance was conducted using 80% confidence intervals, appropriate in the context of a pilot trial. Results A total of 94 participants were randomized, 45 in ACT and 49 in TAU. Follow-up was achieved with 98 and 88%, respectively at 12 months. Those in ACT had better treatment engagement, and were more often seen in their homes or local community than TAU participants. At 12 months the ACT group had more problems related to drinking and lower quality of life than TAU but no differences in drinking measures. The ACT group had a higher percentage of days abstinent but lower quality of life at 6 months. The ACT group had less unplanned healthcare use than TAU. Conclusions An trial of ACT was feasible to implement in an alcohol dependent treatment population. Trial registration ISRCTN22775534
酒精依赖者的自信社区治疗:一项随机对照试验
摘要目的通过一项随机对照试验(RCT)评估自信社区治疗(ACT)治疗成人酒精依赖的可行性和潜在疗效。方法对参加专业社区酒精治疗服务的酒精依赖成人(18岁以上)进行为期12个月的ACT加常规治疗(TAU)与单独TAU治疗的单盲、随机对照试验。ACT的目标是在12个月的时间里,通过自信、定期、每周最少的接触,积极地吸引参与者。ACT联合TAU。TAU包括获得社区团队提供的全方位服务。主要结果是在12个月随访时,每个饮酒日的平均饮酒量和戒酒天数百分比。协方差分析使用80%的置信区间进行,适合于试点试验的背景。结果共94例受试者,ACT组45例,TAU组49例。12个月随访率分别为98%和88%。ACT的参与者有更好的治疗参与,并且比TAU参与者更经常出现在他们的家中或当地社区。在12个月时,ACT组比TAU组有更多与饮酒有关的问题和更低的生活质量,但在饮酒测量方面没有差异。ACT组在6个月时的戒断天数百分比较高,但生活质量较低。ACT组的计划外医疗保健使用少于TAU组。结论:在酒精依赖治疗人群中实施ACT试验是可行的。试验注册号ISRCTN22775534
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