Vasodilatory shock in 15 years old girl in Bulgaria

Adriana Hadzhieva
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Abstract

Background Multisystem Inflammatory Syndrome in children related to COVID-19 (MIS-C) is a new condition the aftermath of which is yet to be studied both in Bulgaria and globally. Up to mid December 2020, world COVID-19 fatalities are put at 1 582 674, according WHO statistics. Case Presentation Summary We present a 15 years old patient with MIS-C, diagnosed with acute abdomen, operated andtreated for septic shock syndrome. The current situation represents a major clinical challenge in part due to the complex differential diagnosis involved: acute abdomen, septic shock, autoimmune diseases (Lupus erythematosus, Juvenile idiopathic arthritis, Kawasaki disease, Acquired immune deficiency, Crohn`s disease, Ulcer colitis), acute myocarditis. At the same time, other symptoms observed in children with COVID-19 such as skin rashes, lymphadenopathy, conjunctivitis are not presented inour patient. We did not observe any myocardial injury, however she went into an acute vasodilatory shock with tachycardia, reduced kidney perfusion pressure and oliguria. Learning Points/Discussion Effects of SARS-CoV-2 infection on patients will be asubject of analysis and clinical research. Differential diagnosisof the multisystem inflammation syndrome in children, clinicalexperience and newtherapeutic strategies are the key to reducing mortality and long-term complicationsin the affected patients.
保加利亚15岁女孩血管扩张性休克
与COVID-19相关的儿童多系统炎症综合征(MIS-C)是一种新的疾病,其后果在保加利亚和全球都有待研究。根据世卫组织的统计数据,截至2020年12月中旬,全球COVID-19死亡人数为1582 674人。我们报告一位15岁的misc患者,诊断为急腹症,手术治疗感染性休克综合征。目前的情况是一个重大的临床挑战,部分原因是由于复杂的鉴别诊断:急腹症、感染性休克、自身免疫性疾病(红斑狼疮、幼年特发性关节炎、川崎病、获得性免疫缺陷、克罗恩病、溃疡性结肠炎)、急性心肌炎。同时,本例患者未出现其他在儿童COVID-19中观察到的症状,如皮疹、淋巴结肿大、结膜炎等。我们没有观察到任何心肌损伤,但她进入急性血管扩张性休克,伴有心动过速,肾灌注压降低和少尿。SARS-CoV-2感染对患者的影响将作为分析和临床研究的主题。儿童多系统炎症综合征的鉴别诊断、临床经验和新的治疗策略是降低患者死亡率和长期并发症的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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