The correlation between intake of energy, protein, fat of underweight and CD4+ count for children with HIV

Waisaktini Maragareth, S. Hadisaputro, A. Margawati
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Pemberian suplementasi zat gizi makro dan mikro dapat meningkatkan status gizi HIV anak yang menjalani ARV.</em><em></em></p><p><strong><em>Tujuan</em></strong><em>: Penelitian ini bertujuan untuk menganalisis hubungan asupan energi, protein, </em><em>dan </em><em>lemak </em><em>terhadap</em><em> status gizi</em><em> berdasarkan berat badan</em><em> dan jumlah CD4</em><em>+</em><em> </em><em>pada HIV anak di Kota dan Kabupaten Semarang. </em></p><p><strong><em>Metode</em></strong><em>: </em><em>Penelitian ini menggunakan desain cross-sectional. Subjek yaitu anak usia 1-14 tahun sebanyak 31 subjek. Data dikumpulkan meliputi tinggi badan (TB), berat badan (BB), asupan zat gizi diperoleh dengan metode food recall 2x24 jam. Jumlah CD4+ melalui pemeriksaan darah subjek. Data dianalisis menggunakan uji Chi-square dan Regresi Logistik untuk menghitung Prevalence Rasio (PR). </em></p><p><strong><em>Hasil</em></strong><em>: </em><em>Asupan protein memberikan risiko bermakna terhadap rendahnya jumlah CD4+ (PR=2,8; p=0,018; CI=1,331-5,891). </em></p><p><strong><em>Kesimpulan</em></strong><em>: Asupan gizi (energi, protein, lemak) tidak terkait dengan berat badan rendah (BB/U) dan </em><em>stunting</em><em> (TB/U). </em><em>A</em><em>supan zat gizi yang berhubungan </em><em>bermakna </em><em>dengan </em><em>jumlah </em><em>CD4+ yang rendah (<500 sel/mm<sup>3</sup>)</em><em> hanya asupan protein.  Asupan protein yang kurang pada HIV anak berisiko mengalami suppresi berat (jumlah CD4+ <500 sel/mm<sup>3</sup>) sebesar 3,036 kali</em></p><p><em><br /> </em><strong>KATA KUNCI<em>:</em></strong><em> asupan </em><em>gizi, HIV anak</em><em> </em><em>, </em><em>jumlah CD4 +,</em><em> </em><em>stunting</em></p><p><strong> </strong></p><p align=\"center\"><strong>ABSTRACT</strong></p><p><strong><em>Background: </em></strong><em>The increase in HIV</em><em>-</em><em>infect</em><em>ed</em><em> children in Indonesia in line with</em><em> the</em><em> increase percentage of HIV</em><em> positive children from mother to child transmission </em><em>from 3% (2013) to 4.6% (2015). 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引用次数: 0

Abstract

ABSTRAK

Latar Belakang: Peningkatan infeksi HIV anak di Indonesia searah dengan peningkatan presentase penularan AIDS dari ibu ke anaknya dari 3% (2013) menjadi 4,6% (2015). HIV anak menjalani terapi antiretroviral (ARV) untuk meningkatkan jumlah sel T-CD4+. Stadium klinis berat pada HIV anak menurunkan jumlah CD4+. Pemberian suplementasi zat gizi makro dan mikro dapat meningkatkan status gizi HIV anak yang menjalani ARV.

Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan asupan energi, protein, dan lemak terhadap status gizi berdasarkan berat badan dan jumlah CD4+ pada HIV anak di Kota dan Kabupaten Semarang.

Metode: Penelitian ini menggunakan desain cross-sectional. Subjek yaitu anak usia 1-14 tahun sebanyak 31 subjek. Data dikumpulkan meliputi tinggi badan (TB), berat badan (BB), asupan zat gizi diperoleh dengan metode food recall 2x24 jam. Jumlah CD4+ melalui pemeriksaan darah subjek. Data dianalisis menggunakan uji Chi-square dan Regresi Logistik untuk menghitung Prevalence Rasio (PR).

Hasil: Asupan protein memberikan risiko bermakna terhadap rendahnya jumlah CD4+ (PR=2,8; p=0,018; CI=1,331-5,891).

Kesimpulan: Asupan gizi (energi, protein, lemak) tidak terkait dengan berat badan rendah (BB/U) dan stunting (TB/U). Asupan zat gizi yang berhubungan bermakna dengan jumlah CD4+ yang rendah (<500 sel/mm3) hanya asupan protein.  Asupan protein yang kurang pada HIV anak berisiko mengalami suppresi berat (jumlah CD4+ <500 sel/mm3) sebesar 3,036 kali


KATA KUNCI: asupan gizi, HIV anak , jumlah CD4 +, stunting

 

ABSTRACT

Background: The increase in HIV-infected children in Indonesia in line with the increase percentage of HIV positive children from mother to child transmission from 3% (2013) to 4.6% (2015). HIV-infected children using antiretroviral therapy (ARV) to increase the T-cells CD4+ count in HIV-infected children patients. Clinical stage heavily on lowering the CD4+ count for HIV-infected children. Supplementation of macro and micronutrients can improve the nutritional status of children using antiretroviral HIV. Objectives. The study aimed to analyze the relationship of intake of energy, protein, fat and clinical stage of  nutritional status and CD4 counts for HIV-infected children in the regional district and the city of Semarang.

Methods: A cross-sectional study in The Regional District and the City of  Semarang. The subject of 31 HIV-infected children aged 1-14 years. Data collected included height, body weight, nutrient intake obtained by the method of Food Recall 2x24 hours. The number of CD4+ through blood test subjects. Data were analyzed using the Chi-Square test.

Results: The intake of protein significantly increase the of low CD4+ count (PR = 3.036; p = 0.021; CI = 1.211 to 7.608 and PR = 2.8; p = 0.018; CI = 1.331 to 5.891). Conclusions: Nutrient intake (energy, protein, fat) is not associated with low body weight (WAZ), stunting (HAZ) and nutrient intake (energy, protein, fat) is not associated with low CD4 + incidence (<500 cells/mm3).

 

KEYWORDS: CD4+ count, HIV-infected children, nutrient intake, stunting 

艾滋病毒感染儿童能量、蛋白质、体重过轻脂肪摄入与CD4+计数的相关性
单向印尼ABSTRAKLatar后面:增加感染艾滋病毒的儿童的百分比增加了传染艾滋病从母亲传给儿子。3%(2013)成为4,6%(2015年)。艾滋病毒儿童接受抗逆转录病毒治疗,以增加T-CD4+细胞的数量。儿童艾滋病毒的重度临床发病率降低了CD4+。礼物营养补充营养物质宏观和微观状态可以提高艾滋病毒的儿童接受抗逆转录病毒药物。目的:本研究旨在分析关系对营养状态的能量、蛋白质和脂肪摄入体重+ CD4细胞计数和根据艾滋病毒和摄政时期三宝垄市的孩子。方法:这项研究采用了分段设计。受试者为14岁至31岁儿童。收集数据包括身高、体重(BB)、营养摄取方法2×24小时的摄取。通过血液检查主题+ CD4数量。数据是用Chi-square测试和物流回归来计算先验比进行分析的。结果:蛋白质摄入对CD4+数量的减少(PR= 2.8;p = 0.018;CI = 1,331-5,891)。结论:营养摄入(能量、蛋白质、脂肪)与低体重(BB/U)和发育不全有关。有意义的营养摄入与低CD4+(3)只摄入蛋白质。蛋白质摄入不足的艾滋病毒风险的孩子度过了艰难suppresi CD4细胞计数(+ 3)3,036倍关键词:营养摄入,HIV + CD4细胞计数,孩子发育迟缓ABSTRACTBackground:《HIV-infected增加,儿童在印度尼西亚in line with The percentage of增长儿童艾滋病毒阳性儿童从母亲到传输从3%(2013年)到4 . 6%(2015年)。hiv -感染儿童使用抗逆转录病毒治疗(ARV)增加T-cells CD4+在hiv受影响的儿童患者中计数。临床舞台非常拥挤,CD4+计数为肝-受感染儿童。宏观和微功能的补充可以通过反转录病毒病毒的方法刺激儿童的营养状态。Objectives。研究报告分析了区域和三宝垄地区影响儿童的能量、蛋白质、脂肪和营养阶段的关系。方法:在三宝垄地区和城市进行跨部门研究。31个受感染儿童的课题为1-14年。收集数据包括身高、身体重量、2×24小时食品召回的营养成分。通过血液测试测试对象CD4+的编号。用chi square测试进行分析。结果:低CD4+计数(PR = 3036;p = 0.021;CI = 1,211至7608和PR = 2.8;p = 0.018;CI = 1.331 to 5.891)。Conclusions: Nutrient进气(能量、蛋白质fat)是美联社(associated with低车身重量(WAZ音符),发育迟缓(哈)和Nutrient进气(能量、蛋白质fat)是音符(associated with低CD4 + incidence(安装:CD4 +伯爵,HIV-infected儿童发育、Nutrient进气
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