A clinicopathological study of sinonasal lesions-5 years study in a rural hospital setup

Savita Dongapure, Anand Anantharao Shankar, R. Parthibhan
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Abstract

Background: Sinonasal lesions of both non-neoplastic and neoplastic variants are frequently observed by clinicians in the nasal cavity and paranasal sinuses. Sinonasal lesions are important due to divergence in their behavior and prognosis. Hence, a careful histological workup remains the mainstay of a final definitive diagnosis and timely intervention. Materials and methods: A prospective analysis was done on 151 patients of Sinonasal masses who presented to the Department of Otorhinolaryngology, MVJ Medical College and Hospital, from 2014 to 2019. Their biodata, clinical profile, and histopathological diagnosis were analyzed. Results: Non-neoplastic lesions (135 cases, 89.4%) were more frequent than neoplastic lesions (16 cases, 10.59%), and showed male predominance with an M: F ratio of 1.7:1. Nasal polyp (119 cases, 88%) was the most common lesion. Nasal obstruction (89 cases 89.45%) was the most common presenting feature. Among the neoplastic lesions, lobular capillary hemangioma was the most common benign lesion (2 cases,50%), and squamous cell carcinoma 2 cases (18.1%), was the most common malignant lesion. Conclusions: Sinonasal masses can present with overlapping clinical features, hence, it is important to categorize them into non-neoplastic and neoplastic lesions for further management. Histopathology remains the gold standard for establishing the diagnosis in such cases.
鼻窦病变的临床病理研究——农村医院5年研究
背景:临床医生在鼻腔和副鼻窦中经常观察到非肿瘤性和肿瘤性鼻窦病变。由于其表现和预后的差异,鼻窦病变很重要。因此,仔细的组织学检查仍然是最终明确诊断和及时干预的支柱。材料与方法:对2014 - 2019年在中山医学院附属附属医院耳鼻咽喉科就诊的151例鼻窦肿物患者进行前瞻性分析。分析他们的生物资料、临床资料和组织病理学诊断。结果:非肿瘤性病变135例(89.4%)多于肿瘤性病变16例(10.59%),且以男性为主,M: F比为1.7:1。鼻息肉(119例,88%)是最常见的病变。鼻塞89例(89.45%)是最常见的临床表现。在肿瘤病变中,小叶毛细血管瘤是最常见的良性病变(2例,50%),鳞状细胞癌是最常见的恶性病变(2例,18.1%)。结论:鼻窦肿块的临床特征可能存在重叠,因此区分非肿瘤性病变和肿瘤性病变对进一步治疗具有重要意义。在这种情况下,组织病理学仍然是建立诊断的金标准。
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