Influenza A and influenza B antibody determination in an Austrian cohort

Clinical Immunology Communications Pub Date : 2022-12-01 DOI:10.1016/j.clicom.2022.09.002

Elisabeth Mara, Johannes Gratzer, Tobias Mader, Thomas Pekar

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Abstract

Influenza is an infectious respiratory disease caused by influenza A and B, which is a virus characterized by a high mutation rate with new strains appearing regularly, making regular booster vaccinations necessary.

In this study, we evaluated the immune status of Influenza A and B by using ELISA. A questionnaire was utilized to appraise the immunization anamnesis and the stance on vaccination.

In total, 202 probands participated in this study. 35.6% of the probands were vaccinated, 10.9% indicated a confirmed influenza infection. 88.1% had a positive influenza A titer, whereas a positive influenza B titer was determined in only 38.6%. Additionally, a correlation between vaccination and titer could be observed.

In this study, we were able to show a higher vaccination rate in our cohort than the Austrian average. Additionally, a higher percentage showed a positive influenza A titer compared to influenza B titer.

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奥地利队列甲型流感和乙型流感抗体测定

流感是一种由甲型和乙型流感引起的传染性呼吸道疾病，甲型和乙型流感是一种病毒，其特点是突变率高，经常出现新的毒株，因此需要定期接种加强疫苗。在这项研究中，我们用ELISA法评估了甲型流感和乙型流感的免疫状态。采用问卷调查的方式评价免疫记忆情况和对疫苗接种的态度。共有202名先证者参与本研究。35.6%的先证者接种了疫苗，10.9%确诊为流感感染。88.1%为甲型流感阳性，38.6%为乙型流感阳性。此外，可以观察到疫苗接种与滴度之间的相关性。在这项研究中，我们能够证明我们的队列中的疫苗接种率高于奥地利的平均水平。此外，a型流感抗体阳性的比例高于B型流感抗体阳性的比例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical Immunology Communications

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