Abstract P197: An anti-HER3 antibody, HMBD-001, that uniquely binds to and blocks the HER3 heterodimerization interface, shows superior tumor growth inhibition in biomarker-defined preclinical cancer models including NRG1-fusion driven cancers

D. Thakkar, Shalini Paliwal, S. Kar, N. Gandhi, Konrad H. Paszkiewicz, P. Ingram, J. Boyd-Kirkup
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引用次数: 3
摘要:抗HER3抗体HMBD-001独特地结合并阻断HER3异源二聚化界面,在生物标志物定义的临床前癌症模型(包括nrg1融合驱动的癌症)中显示出卓越的肿瘤生长抑制作用
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