Abstract P018: Integrative proteomics of PARP1 protein complexes and post-translational modifications implicates DDR and AKT-mTOR signaling in mediating response or primary resistance of ovarian carcinoma cells to PARP1 inhibitors

Ou Deng, Sweta Dash, Thales C. Nepomuceno, B. Fang, D. Marchion, J. Koomen, A. Monteiro, U. Rix
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摘要P018: PARP1蛋白复合物的整合蛋白质组学和翻译后修饰暗示DDR和AKT-mTOR信号传导介导卵巢癌细胞对PARP1抑制剂的反应或原发性耐药
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