Finite Element Analysis for Type B Aortic Dissection Treated with Two Types of Stent Grafts

Q4 Biochemistry, Genetics and Molecular Biology

Molecular & Cellular Biomechanics Pub Date : 2019-02-21 DOI:10.32604/MCB.2019.05706

Zhuangyuan Meng, T. Ma, Shengzhang Wang, Z. Dong, W. Fu

引用次数: 2

Abstract

Retrograde type A dissection (RTAD) and stent graft-induced new entry (SINE) is one of the most common post-TEVAR complications, and is defined as a new tear caused by the stent-graft itself (Dong Z.H. et al., 2009). Presumably, the mechanical action and potential damage of stent-graft to the aorta is related to the stent-graft and the anchoring position, mainly from two aspects: (1) The metal skeleton functions to fix the whole support to the wall of the aorta because it is self-inflating and strong in radial force. (2) After implantation, the stent-graft is bent into the arch like a bent spring, with a tendency to be straight. This may result in elastic recoil force to the aortic wall. This study investigated the occurring reasons of new lesions from the biomechanical and mechanobiological view when stent-grafts were implanted into the true lumen to treat an aortic dissection.

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两种支架治疗B型主动脉夹层的有限元分析

逆行A型夹层(RTAD)和支架诱导的新进入(SINE)是tevar术后最常见的并发症之一，定义为由支架本身引起的新撕裂(董正华等，2009)。推测，支架对主动脉的机械作用和潜在损伤与支架和锚定位置有关，主要有两个方面:(1)金属骨架具有自充气式和强大的径向力，起着将整个支架固定在主动脉壁上的作用。(2)植入后，移植物像弯曲的弹簧一样弯曲入弓内，有伸直的趋势。这可能导致对主动脉壁产生弹性反冲力。本研究从生物力学和力学生物学的角度探讨了主动脉夹层支架植入真腔治疗时新病变发生的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular & Cellular Biomechanics CELL BIOLOGYENGINEERING, BIOMEDICAL&-ENGINEERING, BIOMEDICAL

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： The field of biomechanics concerns with motion, deformation, and forces in biological systems. With the explosive progress in molecular biology, genomic engineering, bioimaging, and nanotechnology, there will be an ever-increasing generation of knowledge and information concerning the mechanobiology of genes, proteins, cells, tissues, and organs. Such information will bring new diagnostic tools, new therapeutic approaches, and new knowledge on ourselves and our interactions with our environment. It becomes apparent that biomechanics focusing on molecules, cells as well as tissues and organs is an important aspect of modern biomedical sciences. The aims of this journal are to facilitate the studies of the mechanics of biomolecules (including proteins, genes, cytoskeletons, etc.), cells (and their interactions with extracellular matrix), tissues and organs, the development of relevant advanced mathematical methods, and the discovery of biological secrets. As science concerns only with relative truth, we seek ideas that are state-of-the-art, which may be controversial, but stimulate and promote new ideas, new techniques, and new applications.