Antibiotic Resistance of Uropathogenic Pseudomonas Aeruginosa

Abstract

Virulent and resistant strains Pseudomonas aeruginosa is one of the most important causes of UTIs in women. The present study was carried to investigate the frequency of virulence factors in the multi-drug resistant strains of P. aeruginosa isolated from women hospitalized due to the UTIs. One hundred urine samples were collected from women patients suffered from UTIs. Samples were cultured and those that were P. aeruginosa positive were analyzed for the presence of putative virulence genes. Sixty two of 100 samples (62/100%) were positive for P. aeruginosa. Monthly, sex and age-dependent prevalence were seen for P. aeruginosa. Bacterial strains had the highest levels of resistance against penicillin (26.6%), imipenem (26.6%) and Trimethoprim (26.6%). Of 62 P. aeruginosa isolates, 25 strains were resistant to more than 10 antibiotics (40.3%). Our findings should raise awareness about antibiotic resistance in hospitalized women with UTIs. Clinicians should exercise caution in prescribing antibiotics, especially in cases of UTIs.