Determination of Lortatadine in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS) and its Pharmacokinetic Application

A. Nagwa, Eslam, S. Erini, H. Sarah
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引用次数: 2

Abstract

Development of simple, rapid, and sensitive assay for the determination of loratadine in order to investigate its pharmacokinetic parameters in human plasma and its application in bioequivalence study of Loratadine 10mg Oral Disintegrated Tablets manufactured locally (test) and originally (Reference).
液相色谱串联质谱法(LC/MS/MS)测定人血浆中氯他他定的含量及其药动学应用
建立简单、快速、灵敏的氯雷他定测定方法,研究其在人血浆中的药动学参数,并应用于国产(试验)和原研(参考)氯雷他定10mg口服崩解片的生物等效性研究。
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