Computational Fluid Dynamics Model Analysis of the Blood Flow in the Right Coronary Artery on the Beating Heart

H. Hayashi, T. Ohashi, D. Mori, T. Yamaguchi
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Abstract

It is very important to elucidate the specific mechanism for the formation, growth, and breakdown of coronary plaque, in order to diagnose and prevent ischemic heart disease, such as myocardial infarction. Coronary atherosclerotic plaque has some characteristic background conditions from a mechanical viewpoint. Of these, the beating motion of the heart wall on which the major coronary arteries are fixed is very interesting, due to its possible mechanical influence on the flow inside the artery, and hence on atherogenesis. This study conducted a computational flow dynamics (CFD) simulation using a simplified model of the right coronary artery, which deforms with contraction of the heart. The right coronary artery was modeled using an ordinary helix, whose torsion and curvature changed in time with the contraction and dilatation of the heart. The results are discussed with respect to local hemodynamics’ characteristics, particularly the wall shear stress distribution.
心脏右冠状动脉血流的计算流体动力学模型分析
阐明冠状动脉斑块形成、生长和分解的具体机制,对诊断和预防缺血性心脏病(如心肌梗死)具有重要意义。从力学角度看,冠状动脉粥样硬化斑块具有一些特征性的背景条件。其中,固定主要冠状动脉的心壁的跳动运动非常有趣,因为它可能对动脉内的流动产生机械影响,从而对动脉粥样硬化产生影响。本研究采用简化的右冠状动脉模型进行了计算流动力学(CFD)模拟,右冠状动脉随心脏收缩而变形。右冠状动脉模型采用普通螺旋结构,其扭转度和曲率随心脏的收缩和扩张而随时间变化。讨论了局部血流动力学特性,特别是壁面剪切应力分布。
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