Hongdai Sun, Yawei Wang, Xue-Jin Huang, Yuanwen Zou
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引用次数: 0
Abstract
Objective
To improve the vitro simulation of the human circulation system under acceleration environment by studying a membrane compliance cavity.
Methods
The vitro simulation of the human circulation system equipped with a membrane cavity wherein the air and liquid was separated by a silicone membrane (0.2 mm or 0.4 mm thick) in order to prevent the gas got into the system as soon as the simulated acceleration caused air-liquid interface tilt. The segmentation of air-liquid interface and deformation of silicone membranes were recorded by a high definition camera when 20 to 200 mmHg pressure applied to the cavity to simulate the acceleration effect. The compliance values at different pressures were calculated.
Results
①No air was found in the closed liquid loop when cavity was pressured. The deformation of 0.2 mm membrane was larger than that of 0.4 mm membrane. ②The membrane compliance cavity showed viscoelasticity feature both in pressure loading and unloading processes. When the cyclic loading was up to 3 times the loading curve of 0.2 mm membrane compliance cavity was almost overlapped on its unloading curve, but they did not coincide for the 0.4 mm membrane. ③The simulation range of 0.2 mm silicone membrane was in 0-1.4 ml/mmHg under 20-200 mmHg test pressures, while 0-0.4 ml/mmHg for 0.4 mm silicone membrane.
Conclusions
The membrane compliance cavity has solved the problem of the air-liquid interface segmentation under the simulated acceleration environment. The simulation range of compliance meets the needs of the vitro simulation for human circulatory system.
Key words:
Acceleration physiology; Blood circulatory; Compliance; In vitro simulation; Silica membrane cavity; Pilots