Methylene Blue Infiltration During Intraoperative Anesthetic Care

Abstract

Following its initial synthesis in 1876, methylene blue has been used in various clinical scenarios for diagnostic and treatment purposes. In general, its adverse effect profile is relatively limited. We present a 22-year-old patient who experienced extravasation of methylene blue intended for intravenous administration during cystoscopy with retrograde pyelogram. The clinical uses of methylene blue are reviewed, risks and adverse effects associated with its administration discussed, and options reviewed for the treatment of inadvertent extravasation