Link between Vitamin D and Cardiovascular Diseases

Abstract

Over the last decades, cardiovascular diseases (CVD) effect is increasing very fast. This review article discuss the association between low level of 25-hydroxy vitamin and cardiovascular diseases. This review also tells us the direct effect of vitamin D on heart or on cardiovascular system may also be involved. Apart from regulating blood pressure, vitamin D also regulate endothelial and smooth muscle cell muscles, most studies support 25 (OH) vitamin D having protective effects on cardiovascular system. However this association of vitamin D and cardiovascular diseases is based on observation & ecological studies and thus is a matter of controversy. Adequate clinical data are not available to confirm these association. Unopposed activation of RAAS & generation of angiotensin promote arterial stiffing & endothelial dysfunction that proceed & contribute to the development of hypertension & also predictors of CVD risk.