Polyherbal Extract Based Linkus Lozenges for Symptomatic Relief: Design, Development and Evaluation

Abstract

Objective: The development of modern dosage form such as lozenges associated with an extended period of local remedy with beneficial therapeutic effect was the objective of this study. The polyherbal extract based lozenges include Viola odorata L, Cordialatifolia L, Menthapiperita L., Adhatodavasica, Glycyrrhizaglabra, Piper longum, Hyssopusofficinalis, Alpiniagalangal which is envisioned for cough and sore throat. Method The preparation of extract, manufacturing of lozenges batch, processing technique with extract based herbal formulation and expansion for analytical standardization including qualitative and quantitative determinations were carried out. Result Vasicine was analysed qualitative and quantified through HPTLC and quantitative analysis of flavonoids by UV visible spectrophotometry, which was not less than 0.02 mg per lozenges and 0.080 mg respectively. Conclusion Current trend of herbal market and the visible financial growth with evident therapeutic graph has proven its effectiveness. Minimum side effects make the herbal and alternative medication more attractive for the end users. This poly herbal extract based lozenges have proven the quality by both protocols including qualitatively via organoleptic attributes and quantitatively by HPTLC and spectrophotometry.