GC-MS analysis of Taraxacum officinale flowers and investigation of antimicrobial, anti-pellicle & anti-biofilm activities

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Main Group Chemistry Pub Date : 2022-04-11 DOI:10.3233/mgc-210133

Shumail Hoor, Tahira Hassan, Barkatullah, S. Khalid, N. Akhtar, A. Al-Qahtani, Afaf A Aldahish, T. Alqahtani, H. M. Alharbi, Reem M Gahtani

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引用次数: 0

Abstract

Plants synthesize large amount of useful and complex products which have no obvious metabolic and growth functions. These complex materials are said to be as secondary metabolites—phytochemicals which are plants active compounds possessing the potential to inhibit diseases. The purpose of the recent study was to investigate the pharmaceutical values of the flowers of Taraxacum officinale, for antimicrobial, anti-pellicle and anti-biofilm properties. Metanolic extracts with chloroform and n-hexane fractions against selected different bacterial (E.coli, P.aeruginosa, S.aureus, S.typhi) and fungal (F.oxysporum, A.niger, A.alternata, A.Terreus) strains were tested and GC-MS, FTIR and HPLC techniques, for detection of various secondary metabolites which are responsible for these activities, were performed. In antimicrobial assay, the result of the methanolic extract and fractions of the flowers was found to be effective against the tested bacterial and fungal strains. The GC-MS and FTIR analysis of chloroform fractions of T. officinale flowers reported the presence of a wide range of phytochemicals and secondery metabolites liable for the biological activities that can be purified in future for the synthesis of noval improved and valuable pharmaceutical products.

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蒲公英花的气相色谱-质谱分析及抗菌、抗膜、抗生物膜活性研究

植物合成大量的有用的复杂产物，这些产物没有明显的代谢和生长功能。这些复杂的物质被称为次生代谢物-植物化学物质，是具有抑制疾病潜力的植物活性化合物。本研究旨在探讨蒲公英花的抗菌、抗膜、抗生物膜等药理价值。采用三氯甲烷和正己烷萃取物对不同细菌(大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌、伤寒沙门氏菌)和真菌(尖孢假单胞菌、黑孢假单胞菌、alternata假单胞菌、terreus假单胞菌)的代谢活性进行了检测，并采用气相色谱-质谱、红外光谱和高效液相色谱技术检测了与这些活性有关的各种次级代谢产物。在抗菌试验中，发现花的甲醇提取物和组分对所测试的细菌和真菌菌株有效。气相色谱-质谱和红外光谱分析表明，officinale花的氯仿部分含有多种具有生物活性的植物化学物质和次生代谢物，这些化学物质和次生代谢物可以在未来用于合成新的改良和有价值的药品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Main Group Chemistry 化学-化学综合

CiteScore

2.00

自引率

26.70%

发文量

审稿时长

>12 weeks

期刊介绍： Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.