Feasibility study of laser-driven neutron sources for pharmaceutical applications

IF 5.2 1区 物理与天体物理 Q1 OPTICS
T. Mori, A. Yogo, Y. Arikawa, T. Hayakawa, S. R. Mirfayzi, Z. Lan, T. Wei, Y. Abe, M. Nakai, K. Mima, H. Nishimura, S. Fujioka, R. Kodama
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引用次数: 0

Abstract

Abstract We predict the production yield of a medical radioisotope ${}^{67}$ Cu using ${}^{67}$ Zn(n, p) ${}^{67}$ Cu and ${}^{68}$ Zn(n, pn) ${}^{67}$ Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+ ${}^9\mathrm{Be}$ and d+ ${}^9$ Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3 $\pm$ 0.5) $\times$ 10 ${}^5$ atoms for ${}^{67}$ Cu, corresponding to a radioactivity of 1.0 $\pm$ 0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated ${}^{67}$ Cu production with a high-frequency laser. The result suggests that it is possible to generate ${}^{67}$ Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.
激光驱动中子源在医药领域应用的可行性研究
摘要利用激光驱动中子源提供的快中子与${}^{67}$ Zn(n, p) ${}^{67}$ Cu和${}^{68}$ Zn(n, pn) ${}^{67}$ Cu的反应,预测了医用放射性同位素${}^{67}$ Cu的产率。中子是由p+ ${}^9\数学{Be}$和d+ ${}^9$ Be与激光等离子体相互作用加速的高能离子反应产生的。我们评估了产率为(3.3 $\pm$ 0.5) $\乘以$ 10 $ ${}^5$ $原子对于${}^{67}$ Cu,对应于单次激光射击Zn箔样品的放射性为1.0 $\pm$ 0.2 Bq。利用模拟结果,我们估计了高频激光的${}^{67}$ Cu产量。结果表明,在医院使用频率为10 Hz,辐射为10,000 s的未来激光系统,可以产生放射性为270 MBq的${}^{67}$ Cu。
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来源期刊
High Power Laser Science and Engineering
High Power Laser Science and Engineering Physics and Astronomy-Nuclear and High Energy Physics
CiteScore
7.10
自引率
4.20%
发文量
401
审稿时长
21 weeks
期刊介绍: High Power Laser Science and Engineering (HPLaser) is an international, peer-reviewed open access journal which focuses on all aspects of high power laser science and engineering. HPLaser publishes research that seeks to uncover the underlying science and engineering in the fields of high energy density physics, high power lasers, advanced laser technology and applications and laser components. Topics covered include laser-plasma interaction, ultra-intense ultra-short pulse laser interaction with matter, attosecond physics, laser design, modelling and optimization, laser amplifiers, nonlinear optics, laser engineering, optical materials, optical devices, fiber lasers, diode-pumped solid state lasers and excimer lasers.
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