CYBERKNIFE ROBOTIC RADIOSURGERY SYSTEM

Saibya Gupta, Priya Gupta
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Abstract

The latest addition to the CyberKnife product family, which was released in September 2009. This review updates the previous technical reviews of the original system version published in the late 1990s. There is a clear dose response for localized prostate cancer radiotherapy and there probablyis a radiobiological rationale for hypo-fractionation. Combining the two should maximize tumor control and increase the therapeutic ratio. Technical developments over the last decade have impacted virtually every aspect of the CyberKnife System. These developments have increased the geometric accuracy of the system and have enhanced the dosimetric accuracy and quality of treatment, with advanced inverse treatment planning algorithms, rapid Monte Carlo dose calculation, and post-processing tools that allow trade-offs between treatment efficiency and dosimetric quality to be explored. The CyberKnife can produce superior DVHs for sparing of rectum and bladder and excellent DVHs for target coverage compared with IMRT, and possesses dose heterogeneities to the same degree as IMRT plans. Keywords: CyberKnife System; Radiosurgery; Stereotactic Body Radiation Therapy; Hypofractionation; IMRT Hetrogeneities
射波刀机器人放射外科系统
最新加入的电子刀产品家族,这是在2009年9月发布。这个审查更新了1990年后期发布的原始系统版本的先前技术审查。局部前列腺癌放射治疗有明确的剂量反应,可能存在低分割的放射生物学原理。两者结合可最大限度地控制肿瘤,提高治疗率。过去十年的技术发展几乎影响了射波刀系统的各个方面。这些发展提高了系统的几何精度,提高了剂量学的精度和治疗的质量,先进的反向治疗计划算法,快速蒙特卡罗剂量计算和后处理工具,允许在治疗效率和剂量学质量之间进行权衡。与IMRT相比,射波刀在保留直肠和膀胱方面可以产生更好的dvh,在目标覆盖方面可以产生更好的dvh,并且具有与IMRT计划相同程度的剂量异质性。关键词:射波刀系统;放射治疗;立体定向放射治疗;辐射;IMRT Hetrogeneities
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