Comparison of Fixation and Uptake of Split Skin Graft Using Autologous Platelet Rich Plasma with Conventional Method for Ulcer

Abstract

Platelet Rich Plasma contains a major Growth factor and has adhesive and healing properties. PRP promotes angiogenesis, collagen synthesis, and wound healing. The main aim of this study is to compare the efficacy of SSG fixation using autologous platelet-rich plasma with the conventional method like suturing. In this study, patients who were admitted with a diagnosis of ”ulcer” in the General Surgery department in SRM medical college hospital and research centre were included and would be taken as subjects for this study. It is a randomized, controlled study with a sample size of 60. Thirty people were put in the autologous PRP group, and another 30 people were put in the suture group. Instant graft uptake of SSG to the ulcer was statistically significant in the PRP group. The seroma formation, the number of dressings and the period of hospital stay were comparatively increased in the suture group than in the PRP. The usage of PRP is secure and efficient in healing ulcer. It has been discovered to be very advantageous in many ways for both the patient and the surgeon. Based on what we found, we recommend using autologous PRP on wounds before resurfacing to help them heal better and faster than suturing.