Firoozeh Akbari Asbagh, Fatemeh Davari tanha, Z. Rezaei, M. Ebrahimi, T. Hemmati, Mojgan Talebbidokhti, Amir Ahmadi, Elham Feizabad
{"title":"Evaluation of the In Vitro Fertilization Success Rate in Transfer of Top-Quality Embryo Versus Poor-Quality Embryos: A Cohort Study","authors":"Firoozeh Akbari Asbagh, Fatemeh Davari tanha, Z. Rezaei, M. Ebrahimi, T. Hemmati, Mojgan Talebbidokhti, Amir Ahmadi, Elham Feizabad","doi":"10.15296/ijwhr.2022.27","DOIUrl":null,"url":null,"abstract":"Objectives: To evaluate the in vitro fertilization success rate by transferring top- versus low-quality embryos. Materials and Methods: This prospective cohort study was conducted on 199 infertile women. Ninety-nine patients underwent an agonist cycle (70 fresh embryo transfer [ET] and 29 frozen ET), and 100 patients received an antagonist cycle (28 fresh ET and 72 frozen ET) in the infertility department of a tertiary university-based hospital between May 2019 and March 2020. The blastocysts classified as AA, AB, and BB, as well as AC, BC, and CC were considered as top- and poor-quality embryos (TQE and PQE). The study outcomes were biochemical and clinical and determined the rate of pregnancy. Results: The average age of the participants was 32.44±5.25 years old. Women with TQE were significantly younger than those with PQE (31.35±4.97 vs. 34.09±5.27, P<0.001). In addition, the duration of women’s infertility was significantly (P<0.001) correlated with the embryo’s top quality. A positive β-human chorionic gonadotropin was detected in 12.6% (n=25) of women while clinical pregnancy was investigated in 8% (n=16) of them. The fetal heart rate was detected in 7.5% (n=15). Eventually, the clinical (P=0.020) and determined (P=0.030) pregnancy rates significantly differed between two study groups with a higher level in the TQE group. Conclusions: It seems that TQP transfer should be the first recommendation for infertile women, but when the double-embryo transfer (DET) is needed according to the patient’s condition, she should be informed that the quality of the second embryo may have an adverse impact on pregnancy consequences.","PeriodicalId":14346,"journal":{"name":"International Journal of Women's Health and Reproduction Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2021-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Women's Health and Reproduction Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15296/ijwhr.2022.27","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"REPRODUCTIVE BIOLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
Objectives: To evaluate the in vitro fertilization success rate by transferring top- versus low-quality embryos. Materials and Methods: This prospective cohort study was conducted on 199 infertile women. Ninety-nine patients underwent an agonist cycle (70 fresh embryo transfer [ET] and 29 frozen ET), and 100 patients received an antagonist cycle (28 fresh ET and 72 frozen ET) in the infertility department of a tertiary university-based hospital between May 2019 and March 2020. The blastocysts classified as AA, AB, and BB, as well as AC, BC, and CC were considered as top- and poor-quality embryos (TQE and PQE). The study outcomes were biochemical and clinical and determined the rate of pregnancy. Results: The average age of the participants was 32.44±5.25 years old. Women with TQE were significantly younger than those with PQE (31.35±4.97 vs. 34.09±5.27, P<0.001). In addition, the duration of women’s infertility was significantly (P<0.001) correlated with the embryo’s top quality. A positive β-human chorionic gonadotropin was detected in 12.6% (n=25) of women while clinical pregnancy was investigated in 8% (n=16) of them. The fetal heart rate was detected in 7.5% (n=15). Eventually, the clinical (P=0.020) and determined (P=0.030) pregnancy rates significantly differed between two study groups with a higher level in the TQE group. Conclusions: It seems that TQP transfer should be the first recommendation for infertile women, but when the double-embryo transfer (DET) is needed according to the patient’s condition, she should be informed that the quality of the second embryo may have an adverse impact on pregnancy consequences.
期刊介绍:
All kind of knowledge contributing to the development of science by its content, value, level and originality will be covered by IJWHR. Problems of public health and their solutions are at the head of the windows opening us to the world. The "International Journal of Women''s Health and Reproduction Sciences” is a modern forum for scientific communication, covering all aspects women health and reproduction sciences, in basic and clinical sciences, mainly including: -Medical Education in Women Health and Reproduction Sciences -Cardiology in Women Health-Related Reproductive Problems -Sports Medicine in Women Health and Reproduction Sciences -Psychiatry in Women Health-Related Reproductive Problems -Antioxidant Therapy in Reproduction Medicine Sciences -Nutrition in Women Health and Reproduction Sciences -Defense Androgen and Estrogen -Fertility and Infertility -Urogynecology -Endometriosis -Endocrinology -Breast Cancer -Menopause -Puberty -Eroticism -Pregnancy -Preterm Birth -Vaginal Diseases -Sex-Based Biology -Surgical Procedures -Nursing in Pregnancy -Obstetrics/Gynecology -Polycystic Ovary Syndrome -Hyperandrogenism in Females -Menstrual Syndrome and Complications -Oncology of Female Reproductive Organs -Traditional Medicine in Women Reproductive Health -Ultrasound in Women Health Reproduction sciences -Stem Cell Research In Women Reproduction Sciences -Complementary Medicine in Women Reproductive Health -Female Sexual Dysfunction: Pathophysiology & Treatment