Development of a 3D-printable matrix using cellulose microfibrils/guar gum-based hydrogels and its post-printing antioxidant activity  

IF 6.8 3区 医学 Q1 ENGINEERING, BIOMEDICAL
Olajide Emmanuel Adedeji, Ju Hyun Min, Gi Eon Park, Hye Jee Kang, Ji-Young Choi, Mariam Omowunmi Aminu, Ocheme Boniface Ocheme, S. Joo, K. Moon, Young Hoon Jung
{"title":"Development of a 3D-printable matrix using cellulose microfibrils/guar gum-based hydrogels and its post-printing antioxidant activity  ","authors":"Olajide Emmanuel Adedeji, Ju Hyun Min, Gi Eon Park, Hye Jee Kang, Ji-Young Choi, Mariam Omowunmi Aminu, Ocheme Boniface Ocheme, S. Joo, K. Moon, Young Hoon Jung","doi":"10.36922/ijb.0164","DOIUrl":null,"url":null,"abstract":"A biomaterial ink suitable for three-dimensional (3D) printing was developed using cellulose microfibrils (CMFs, 1% w/v) and guar gum (1–7 g/100 mL CMFs), and the post-printing stability and antioxidant functionality of the borax-treated construct were investigated. Rheological analysis, Fourier transform infrared spectrometry, X-ray diffractometry, and scanning electron microscopy revealed the suitability of the two polymers to form an interpenetrating composite hydrogel that would facilitate printability. The produced composite hydrogel showed good structural, morphological, thermal, and textural properties. CMFs with 5% guar gum showing optimal surface properties and rheological properties were printed with the least dimensional errors at 50% infill density, 10 mm/s printing speed, 0.8 mm nozzle diameter, and 0.5 mm layer height. The treatment with borax showed good shape fidelity during 12 h storage. The treated construct also showed considerably increased mechanical properties and antioxidant activities in comparison with the untreated construct. A stable 3D construct suitable for a variety of applications could be produced using CMFs and guar gum-based ink.","PeriodicalId":48522,"journal":{"name":"International Journal of Bioprinting","volume":null,"pages":null},"PeriodicalIF":6.8000,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Bioprinting","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.36922/ijb.0164","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

Abstract

A biomaterial ink suitable for three-dimensional (3D) printing was developed using cellulose microfibrils (CMFs, 1% w/v) and guar gum (1–7 g/100 mL CMFs), and the post-printing stability and antioxidant functionality of the borax-treated construct were investigated. Rheological analysis, Fourier transform infrared spectrometry, X-ray diffractometry, and scanning electron microscopy revealed the suitability of the two polymers to form an interpenetrating composite hydrogel that would facilitate printability. The produced composite hydrogel showed good structural, morphological, thermal, and textural properties. CMFs with 5% guar gum showing optimal surface properties and rheological properties were printed with the least dimensional errors at 50% infill density, 10 mm/s printing speed, 0.8 mm nozzle diameter, and 0.5 mm layer height. The treatment with borax showed good shape fidelity during 12 h storage. The treated construct also showed considerably increased mechanical properties and antioxidant activities in comparison with the untreated construct. A stable 3D construct suitable for a variety of applications could be produced using CMFs and guar gum-based ink.
利用纤维素微纤维/瓜尔胶基水凝胶开发3d可打印基质及其打印后抗氧化活性
采用纤维素微纤维(CMFs, 1% w/v)和瓜尔胶(1-7 g/100 mL CMFs)制备了一种适合三维打印的生物材料墨水,并研究了硼砂处理结构体的打印后稳定性和抗氧化功能。流变分析、傅里叶变换红外光谱、x射线衍射和扫描电子显微镜显示了这两种聚合物形成互穿复合水凝胶的适宜性,这将有利于印刷。制备的复合水凝胶具有良好的结构、形态、热性能和织构性能。在填充密度为50%、打印速度为10 mm/s、喷嘴直径为0.8 mm、层高为0.5 mm的条件下,打印出具有最佳表面性能和流变性能的5%瓜尔胶复合材料,尺寸误差最小。硼砂处理在12 h的贮藏过程中表现出良好的保真度。与未处理的结构相比,处理后的结构也显示出显著增加的机械性能和抗氧化活性。使用CMFs和瓜尔胶基油墨可以产生适合各种应用的稳定3D结构。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
6.90
自引率
4.80%
发文量
81
期刊介绍: The International Journal of Bioprinting is a globally recognized publication that focuses on the advancements, scientific discoveries, and practical implementations of Bioprinting. Bioprinting, in simple terms, involves the utilization of 3D printing technology and materials that contain living cells or biological components to fabricate tissues or other biotechnological products. Our journal encompasses interdisciplinary research that spans across technology, science, and clinical applications within the expansive realm of Bioprinting.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信