IMPACT OF INFLAMMATORY BOWEL DISEASE AND DISEASE ACTIVITY ON THE QUALITY OF LIFE, A SINGLE CENTER STUDY

Abstract

Inflammatory bowel disease (IBD) is a group of chronic relapsing inflammatory conditions of the gastrointestinal tract. Inflammatory bowel disease has a substantial impact on quality of life. It causes considerable personal, emotional, and social burdens. The impact of IBD on quality of life places a significant burden on the patient and caregivers. The study assessed the impact of inflammatory bowel disease and disease activity on quality of life of the patients. This cross-section study was conducted on 88 patients with inflammatory bowel disease who attended the IBD Clinic, Ain Shams University Hospitals. An informed consent was obtained from each patient. All patients were subjected to clinical assessment, laboratory investigations, colonoscopy, assessment of disease activity and assessment of quality of life using PCASEE score. The eighty-eight inflammatory bowel disease patients were divided into: disease group 40 (45.5%) patients, and G2: ulcerative colitis (UC) group 48 (54.5%) patients. They were 39 (44.3%) males and 49 (55.7 %) females, with ages ranged between 19 and 52 years old (mean 33). The result showed negative significant correlation between clinical and endoscopic activity in UC group measured by simple clinical colitis activity index and Mayo score respectively and quality of life scores in the patients with P <0.001. In CD, there was negative significant corre-index with P <0.001, but without endoscopic activity. There was no significant effect of inflammatory bowel disease on quality of life of the patients especially during disease activity.