Photodynamic Therapy for Oral Candidosis: a new option?

Abstract

Candida Albicans is a ubiquitous polymorphic fungus that is part of the normal microbiota of the gastrointestinal and reproductive tracts of healthy individuals. In order to colonize the oral mucosa C. albicans must adhere to the epithelial cell lining while avoiding being killed by host antimicrobial factors. This infection occurs in a diverse group of patients that have some risk factor such as the use of dentures, corticosteroid inhalers, cigarettes, broad-spectrum antibiotics, and immunosuppressive and chemotherapeutic agents. Patients with HIV, diabetes, and iatrogenic or autoimmune-induced dry mouth are also at substantial risk for Oral Candidosis [1].