The Anti-Inebriation of Probiotic Fermented Pollen on Acute Alcoholism Rats and Protection on Alcoholic Liver Injury

Abstract

With acute alcoholism rats as the research object, the disappearance and recovery time of righting reflex, β -endomorpHin ( β -EP) in brain tissue, Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) levels, liver antioxidant indexes were measured to explore the anti-inebriation on acute alcoholism rats and protection on alcoholic liver injury by probiotic fermented pollen. The results showed that compared with the model group, probiotic fermented pollen could increase tolerance time and decrease sobering up time, reduce the level of β -EP in the brain tissue of rats, protect the integrity of cell membrane in the liver, improve the activity of Alcohol dehydrogenase (ADH) and Aldehyde dehydrogenase (ALDH), improve the activity of Superoxide dismutase (SOD) in the liver, improve the level of Glutathione (GSH), reduce the level of Malonyldialdehyde (MDA). Probiotic fermented pollen had anti-inebriation on acute alcoholism rats and protection on alcoholic liver injury.