{"title":"Investigation of formation and ultrasonic disassembling of RBC Aggregation aimed for maintenance of blood channel","authors":"Mayu Hatakeyama, Yuichiro Akamatsu, Takayuki Sato","doi":"10.1002/ecj.12371","DOIUrl":null,"url":null,"abstract":"<p>Establishment of real-time monitoring technique for blood viscosity during extracorporeal circulation treatment is needed. We have demonstrated that red blood cell (RBC, hereafter) aggregation degree, which highly correlates with the blood viscosity, can be estimated by the ultrasound spectroscopic observation of the RBC and the defining of the peak frequency by the Fast Fourier Transform process. In this study, the peak frequency was measured to investigate the aggregation degree of RBC flowing in a simple heart-lung machine. In addition, to disassemble the RBC aggregations that might cause the clogging of the circuit, a disassemble technique of the RBC aggregations using a focused 5 MHz ultrasonic transducer was also proposed. As the first step of this study, the disassembling of the RBC aggregations was carried out under the still condition and its effect was confirmed by the peak frequency method.</p>","PeriodicalId":50539,"journal":{"name":"Electronics and Communications in Japan","volume":"105 3","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electronics and Communications in Japan","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ecj.12371","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0
Abstract
Establishment of real-time monitoring technique for blood viscosity during extracorporeal circulation treatment is needed. We have demonstrated that red blood cell (RBC, hereafter) aggregation degree, which highly correlates with the blood viscosity, can be estimated by the ultrasound spectroscopic observation of the RBC and the defining of the peak frequency by the Fast Fourier Transform process. In this study, the peak frequency was measured to investigate the aggregation degree of RBC flowing in a simple heart-lung machine. In addition, to disassemble the RBC aggregations that might cause the clogging of the circuit, a disassemble technique of the RBC aggregations using a focused 5 MHz ultrasonic transducer was also proposed. As the first step of this study, the disassembling of the RBC aggregations was carried out under the still condition and its effect was confirmed by the peak frequency method.
期刊介绍：
Electronics and Communications in Japan (ECJ) publishes papers translated from the Transactions of the Institute of Electrical Engineers of Japan 12 times per year as an official journal of the Institute of Electrical Engineers of Japan (IEEJ). ECJ aims to provide world-class researches in highly diverse and sophisticated areas of Electrical and Electronic Engineering as well as in related disciplines with emphasis on electronic circuits, controls and communications. ECJ focuses on the following fields:
- Electronic theory and circuits,
- Control theory,
- Communications,
- Cryptography,
- Biomedical fields,
- Surveillance,
- Robotics,
- Sensors and actuators,
- Micromachines,
- Image analysis and signal analysis,
- New materials.
For works related to the science, technology, and applications of electric power, please refer to the sister journal Electrical Engineering in Japan (EEJ).
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