Prevalence and antibiotic susceptibility pattern of uropathogens causing urinary tract infection among pregnant women in Ujjain M.P. (India)

Kaina Bhonsle, A. Vyas, H. Vyas, Abhiraj Ramchandani, K. Hemwani
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Abstract

Urinarytract infection is one of the most prevalent frequently found disorders in pregnant women caused by bacteria and if it is not diagnosed then untreated UTI can causes serious maternal and fetal complications. The purpose of this work was to study the prevalence of urinary tract infection among pregnant women of Ujjain and to identify uropatogens and their antibiotic susceptibility pattern in pregnant women of Ujjain. A total of 120 midstream urine samples of pregnant women were collected aseptically and cultured on different growth media. The isolated bacteria were identified by standard microbiological procedure and the antibiotic susceptibility pattern was recorded using Kirby-Bauer disc diffusion method. Out of 120 urine samples, 78 samples tested positive for UTI suggesting that (65%) of pregnant women suffered from UTI and most prevalent bacterial pathogen was (41.0%) followed by (23.0%), (11.5%), (14.1%) and (10.2%). Majority of the isolated uropathogens were showing high sensitivity towards Doripenem, Meropenem and Imipenem while very less sensitivity towards Ampicillin and Penicillin. The study shows high prevalence of UTI among pregnant women and occurrence of high resistance towards antibiotics. So routine screening of the pregnant women having UTI and proper selection of antibiotic for treatment is needed for reducing the risk of serious complications during pregnancy.
印度Ujjain M.P.孕妇尿路感染尿路病原体患病率及抗生素敏感性分析
尿路感染是由细菌引起的孕妇最常见的疾病之一,如果未得到诊断,则未经治疗的尿路感染可导致严重的母婴并发症。本研究旨在了解乌贾因省孕妇尿路感染的流行情况,了解乌贾因省孕妇尿路病原菌及其药敏模式。采用无菌法采集孕妇中游尿液120份,在不同培养基上培养。采用标准微生物学方法鉴定分离菌,采用Kirby-Bauer圆盘扩散法记录药敏谱。在120份尿样中,78份尿样尿路感染检测呈阳性,表明(65%)孕妇患有尿路感染,最常见的细菌病原体为(41.0%),其次是(23.0%)、(11.5%)、(14.1%)和(10.2%)。大多数尿路病原菌对多利培南、美罗培南和亚胺培南敏感性高,对氨苄西林和青霉素敏感性极低。该研究表明,孕妇中尿路感染的患病率很高,对抗生素的耐药性也很高。因此,需要对患有尿路感染的孕妇进行常规筛查,并正确选择抗生素进行治疗,以减少妊娠期间严重并发症的风险。
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