The Role of Coagulation Mechanism in the Development of Acute Thrombosed Hemorrhoidal Disease

Selman Alkan, M. Çakır, A. Varman, Mustafa Şentürk, O. Kişi, A. Topal
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Abstract

ABSTRACT Background Hemorrhoidal disease is a common benign anorectal disease. Acute thrombosis that occurs during the course of hemorrhoidal disease is a painful complication. Factors affecting its etiopathogenesis are not known definitively. The aim of this study, therefore, was to assess predisposition to coagulation during the development of the disease. Method 30 patients with acute thrombosed hemorrhoidal disease and 30 other patients with hemorrhoidal disease but no thromboses were included in the study. Samples collected from these patients were analyzed with thromboelastography machines. The results were compared with patients’ demographic data. Results No statistically significant difference was found between the groups as per age, sex, diarrhea, history of a similar attack, history of surgical treatment, spicy food consumption, fibrous food consumption, and regular exercise. The results of our study revealed that the alpha angle was smaller in patients with acute thrombosed hemorrhoidal disease. Conclusion Hypercoagulability does not occur in patients with acute thrombosed hemorrhoidal disease
凝血机制在急性血栓性痔疮病发展中的作用
背景痔疮病是一种常见的良性肛肠疾病。急性血栓形成发生在痔疮疾病的过程中是一个痛苦的并发症。影响其发病机制的因素尚不明确。因此,本研究的目的是评估疾病发展过程中的凝血倾向。方法选取30例急性血栓性痔疮患者和30例非血栓性痔疮患者作为研究对象。从这些患者身上收集的样本用血栓弹性成像仪进行分析。结果与患者的人口统计数据进行比较。结果年龄、性别、腹泻史、类似发作史、手术治疗史、食用辛辣食物、食用纤维性食物、经常运动等方面各组间无统计学差异。我们的研究结果显示,急性血栓性痔疮患者的α角较小。结论急性血栓性痔疮患者不存在高凝现象
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