Recent advance in statins in post-stroke epilepsy

Abstract

Post-stroke epilepsy (PSE), as one of the common complications after stroke, often seriously affect the quality of life of the survivors. In recent years, more and more studies have found that statins can protect the integrity of blood-brain barrier, alleviate excitotoxic damage of neurotransmitters, reduce neuronal apoptosis, and reduce neuroinflammation, which play a role in brain protection, thereby reducing the risk of PSE. This article reviews the treatment of PSE and application of statins in PSE. Key words: Stroke; Epilepsy; Statins