The Progress of Common Treatments and Research for Androgenetic Alopecia

Abstract

Androgenetic alopecia (AGA) is the most common type of hair loss, in which patients mostly present with a state of a receding hairline on the forehead. It brings a great mental burden to the patient. Androgenetic alopecia is caused by the combination of dihydrotestosterone (DHT) and androgen receptors (AR), disrupting the hair follicle cycle and minimizing hair follicles. The major treatments currently available include finasteride, minoxidil, hair transplantation, Platelet-rich plasma (PRP), stem cell therapy, etc. This article reviews the mechanism of AGA and the existing major treatments. The author suggested that androgen receptor degrader drugs have good prospects for application among those of various therapeutic options.